Thoracic Key

Fig. 15.1 Circulating and resident cells involved in neoangiogenesis. This figure depicts the rare circulating low proliferative potential (LPP) and high proliferative potential endothelial colony forming cells (HPP-ECFC) that may…

Fig. 12.1 Growth and development of the lung are mechanically coupled to that of the thorax. Adapted from [5] Innate Potential for Compensatory Lung Growth Lower vertebrates such as newts…

Fig. 17.1 The stages of tracheal and lung development in human and mouse. Genetic regulation of mouse tracheal specification from foregut endoderm (Bmp4) and patterning (Shh) is indicated in bottom…

Tracheoesophageal fistula/esophageal atresia Congenital acinar hypoplasia Congenital alveolar hypoplasia Surfactant deficiency Bronchopulmonary dysplasia Cystic fibrosis Neuroendocrine hyperplasia of infancy Chronic obstructive pulmonary disease Asthma Idiopathic pulmonary fibrosis Infectious disease Cystic…

Fig. 11.1 Second Harmonic Generation images of airway and parenchymal tissues from non-diseased and diseased lungs. Second Harmonic Generation signals from fibrillar collagen I propagated in the forward (Cyan) (representing…

Fig. 4.1 Development of the lung buds in the early chick embryo. At HH stage 17 (day 2.5) the laryngotracheal groove forms in the ventral foregut (F) and deepens over…

Fig. 18.1 Schematic of ex vivo organ engineering. Autologous cells are obtained by a biopsy from the eventual transplant recipient and expanded in ex vivo culture. A scaffold, either synthetic…

Fig. 1.1 A complete developmental history of SOX9 lung epithelial progenitors. Optical projection tomography (OPT, top row, scale: 250 um) and confocal images (bottom row, scale: 20 um) of immunostained…

Fig. 5.1 Histological representation of the alveolar region of a lung from (a; ×25 magnification) a term infant, and (b; ×50 magnification) a surfactant -treated preterm infant with BPD. Photomicrographs…