Histiocytic disorder Morphology Immunophenotype Reactive histiocytic conditions Non-specific interstitial pneumonitis Polymorphous infiltrate containing macrophages Bronchiolar obstruction Foamy cells Healing process Infections Mycobacteria infections Foamy histiocytes PAS+/Ziehl+ Whipple disease Foamy histiocytes…
Infectious diseases Invasive aspergillosis Chronic necrotising pulmonary aspergillosis/Aspergilloma Hypersensitivity diseases Aspergillus sensitisation in asthma And severe asthma associated with fungal sensitization (SAFS) Hypersensitivity pneumonitis Allergic bronchopulmonary aspergillosis Aspergillus: An Ubiquitous…
HRCT technical requirements Scans without contrast Full inspiration without respiratory motion Contiguous or noncontiguous axial scans with thin sections, reconstructed at ≤2 cm intervals Reconstructed slice collimation ≤2 mm High…
Clinical findings CBD Sarcoidosis Onset Insidious Acute or insidious Restrictive lung disease Yes Yes Obstructive lung disease Frequent Yes Reduced diffusion capacity Yes Yes Erythema nodosum No Yes Lupus pernio…
Fig. 20.1 Cases of pulmonary alveolar microlithiasis in the international literature: subdivision by continent (656 pts. out of 670) Table 20.1 Cases of pulmonary alveolar microlithiasis from 56 countries Algeria…
Pattern of DI involvement Typical timing to onset Develops in Typical drugs or compoundsa Main complications Angioedema and UAO Immediate-to-late min-h ACEI, ARB UAO, throat closure, locked airway, asphyxia Anaphylaxis…
Fig. 27.1 High resolution computed tomographic image demonstrating bilateral, peripheral predominant ground glass opacifications suggestive of non-specific interstitial pneumonia Does this patient have connective tissue disease-associated interstitial lung disease? Introduction…
Type 1 HP (e.g., farmer’s lung) Type 2 HP (e.g., bird fancier-s lung) Exposure Usually massive and intermittent Usually chronic insidious Usually microorganisms (fungi and actinomycetes) Usually lowdose of…
Fig. 6.1 The flow volume loop in fixed central airway obstruction reveals blunting of both the inspiratory and expiratory portions of the loop Conventional chest X-rays are neither sensitive nor…
Fig. 36.1 Hermansky-Pudlak syndrome. CT images through upper and lower lung zones showing extensive subpleural honeycombing bilaterally, more prominent in the lower lung zones where ground glass opacity is also…
