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Asthma Clinic: Putting It All Together

Nov 7, 2020 by in Uncategorized Comments Off on Asthma Clinic: Putting It All Together

Purpose of a high-risk clinic Address diagnostic uncertainties Recognize and manage factors that make asthma “difficult to treat”  Persistent triggers  Suboptimal adherence and inhaler technique  Uncontrolled comorbidities Optimize self-management skills…

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in Severe Asthma

Nov 7, 2020 by in Uncategorized Comments Off on in Severe Asthma

Fig. 7.1 The five adult clinical cluster phenotypes from the Severe Asthma Research Program (SARP) with the predominant clinical characteristics. (Reprinted with permission of the American Thoracic Society. Copyright ©…

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and Management of Work-Related Asthma

Nov 7, 2020 by in Uncategorized Comments Off on and Management of Work-Related Asthma

Most common agents for occupational asthma Workers at risk of exposure Isocyanates Rigid or flexible polyurethane foam makers, polyurethane foam insulation installers, urethane spray painters, users of adhesives Flour Bakers,…

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Considerations in Management of Allergic Asthma

Nov 7, 2020 by in Uncategorized Comments Off on Considerations in Management of Allergic Asthma

Fig. 9.1 Induction of TH2 cells . TSLP, IL-25, and IL-33 produced by respiratory epithelium on exposure to respiratory allergens, pollutants, or viruses promote the induction of allergen-specific TH2 cells….

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Asthma: Unmet Needs and Future Directions

Nov 7, 2020 by in Uncategorized Comments Off on Asthma: Unmet Needs and Future Directions

!DOCTYPE html> © Springer Nature Switzerland AG 2020S. Khurana, F. Holguin (eds.)Difficult To Treat AsthmaRespiratory Medicinehttps://doi.org/10.1007/978-3-030-20812-7_16 16. Difficult Asthma: Unmet Needs and Future Directions Shu-Yi Liao1  , Amir A. Zeki1   and Nizar Jarjour2   (1) Division of Pulmonary, Critical…

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Asthma in Pregnancy: Special Considerations

Nov 7, 2020 by in Uncategorized Comments Off on Asthma in Pregnancy: Special Considerations

Parameter Changes in pregnancy Respiratory rate Unchanged Minute ventilation Increases by 30–50% Tidal volume (Vt) Increases by 40% Oxygen consumption Increases by 20% Forced expiratory volume in 1 s (FEV1) Unchanged…

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Considerations in Management of Non-eosinophilic Asthma

Nov 7, 2020 by in Uncategorized Comments Off on Considerations in Management of Non-eosinophilic Asthma

Fig. 11.1 Practical therapeutic approach to non-eosinophilic asthma. (LAMA Long-acting antimuscarinic antagonist, LABA Long-acting beta agonists, SABA Short-acting beta agonists, TSLP Thymic stromal lymphopoietin) The first step is to confirm…

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in Inhaled Medications

Nov 7, 2020 by in Uncategorized Comments Off on in Inhaled Medications

  ICS/LABA (n = 17,537) ICS (n = 17,552) ICS/LABA vs. ICS hazard ratio (95% confidence interval) Serious asthma-related events Death Intubation Hospitalization 116 2 1 115 105 0 2 105 1.10 (0.85–1.44) Adapted…

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Blood Pressure Variability

Oct 30, 2020 by in Uncategorized Comments Off on Blood Pressure Variability

Fig. 14.1 Different types of blood pressure variability, their determinants, and prognostic relevance. Taken from [2] by permission. ∗Assessed in laboratory conditions; ‡cardiac, vascular, and renal subclinical organ damage; §blood…

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