Diabetes and Cardiac Mitochondria
(1) The Molecular Cardiology and Neuromuscular Institute, Highland Park, NJ, USA Abstract Heart failure is common in patients with diabetes, even in the absence of coronary artery disease or…
Heart Mitochondrial ROS and Oxidative Stress
(1) The Molecular Cardiology and Neuromuscular Institute, Highland Park, NJ, USA Abstract Under pathophysiological conditions, reactive oxygen species (ROS) levels may increase and cause cell damage and dysfunction targeting…
Role of Mitochondria in Ischemia and Cardioprotection
(1) The Molecular Cardiology and Neuromuscular Institute, Highland Park, NJ, USA Abstract Ischemia and postischemic reperfusion cause a wide array of functional and structural alterations of mitochondria. Although mitochondrial…
Mitochondrial Dynamics in Health and Disease
(1) The Molecular Cardiology and Neuromuscular Institute, Highland Park, NJ, USA Abstract The two opposing highly regulated processes, division (fission) and fusion, determine cell-type-specific mitochondrial morphology, intracellular distribution, and…
Mitochondria and Cardiac Dysrhythmias
(1) The Molecular Cardiology and Neuromuscular Institute, Highland Park, NJ, USA Abstract Ventricular dysrhythmias represent the most predominant etiology of sudden cardiac death throughout the world. However, the mechanisms…
Mitochondria in the Aging Heart
(1) The Molecular Cardiology and Neuromuscular Institute, Highland Park, NJ, USA Abstract Aging is associated with progressive impairment of a variety of vital functions, resulting in an increased vulnerability…
The Role of Mitochondria in Atherosclerosis
(1) The Molecular Cardiology and Neuromuscular Institute, Highland Park, NJ, USA Abstract Mitochondria are both sources and targets of reactive oxygen species, and there is increasing evidence that mitochondrial…
Introduction to Mitochondria in the Heart
(1) The Molecular Cardiology and Neuromuscular Institute, Highland Park, NJ, USA Abstract In this introductory chapter to Mitochondria Role in Cardiovascular Diseases, we will discuss those primary defects in…
Stem Cells and Mitochondria
(1) The Molecular Cardiology and Neuromuscular Institute, Highland Park, NJ, USA Abstract Stem cells are undifferentiated cells characterized by the presence of the potential for self-renewal and the unique…
The Role of Mitochondria in Hypertension
(1) The Molecular Cardiology and Neuromuscular Institute, Highland Park, NJ, USA Abstract Hypertension is a major public health problem and is one of the most important risk factors for…
