Methotrexate and Risk of Cardiovascular Disease

Dec 15, 2016 by in CARDIOLOGY Comments Off on Methotrexate and Risk of Cardiovascular Disease

The systematic review and meta-analysis by Micha et al addresses a clinically important issue. Methotrexate is the most common disease-modifying antirheumatic drug prescribed in patients with rheumatoid arthritis (RA). Unfortunately,…

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Effect of Timing of Chronic Preoperative Aspirin Discontinuation on Morbidity and Mortality in Patients Having Combined Coronary Artery Bypass Grafting and Valve Surgery

Dec 15, 2016 by in CARDIOLOGY Comments Off on Effect of Timing of Chronic Preoperative Aspirin Discontinuation on Morbidity and Mortality in Patients Having Combined Coronary Artery Bypass Grafting and Valve Surgery

We read with interest the study by Jacob et al. Its objective was to determine if late use of aspirin before coronary artery bypass grafting (CABG) with valve surgery affects…

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N-Terminal Pro-Brain Natriuretic Peptide and Angiotensin-Converting Enzyme-2 Levels and Their Association With Postoperative Cardiac Complications After Emergency Orthopedic Surgery

Dec 15, 2016 by in CARDIOLOGY Comments Off on N-Terminal Pro-Brain Natriuretic Peptide and Angiotensin-Converting Enzyme-2 Levels and Their Association With Postoperative Cardiac Complications After Emergency Orthopedic Surgery

The prognostic usefulness of the cardiac biomarkers N-terminal pro-brain natriuretic peptide (NT-proBNP) and angiotensin-converting enzyme 2 (ACE-2), in predicting adverse cardiac outcomes after orthopedic surgery is not well studied. The…

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Ventricular Structure and Function in Children With Sickle Cell Disease Using Conventional and Tissue Doppler Echocardiography

Dec 15, 2016 by in CARDIOLOGY Comments Off on Ventricular Structure and Function in Children With Sickle Cell Disease Using Conventional and Tissue Doppler Echocardiography

Conventional 2-dimensional, M-mode, and spectral Doppler echocardiographic techniques have documented abnormal ventricular function in adults with sickle cell disease (SCD), but assessments in children are conflicting. Tissue Doppler echocardiography (TDE)…

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Hemodynamic Characteristics and Predictors of Pulmonary Hypertension in Patients With Sickle Cell Disease

Dec 15, 2016 by in CARDIOLOGY Comments Off on Hemodynamic Characteristics and Predictors of Pulmonary Hypertension in Patients With Sickle Cell Disease

Pulmonary hypertension is a common co-morbidity of sickle cell disease with an associated increased mortality risk, but its etiology is not well-understood. To evaluate the hemodynamic characteristics, clinical predictors, and…

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Long-Term (5- to 20-Year) Outcomes After Transcatheter or Surgical Treatment of Hemodynamically Significant Isolated Secundum Atrial Septal Defect

Dec 15, 2016 by in CARDIOLOGY Comments Off on Long-Term (5- to 20-Year) Outcomes After Transcatheter or Surgical Treatment of Hemodynamically Significant Isolated Secundum Atrial Septal Defect

Truly long-term follow-up data after transcatheter closure (TC) of atrial septal defects (ASDs) are scarce. We report the 5- to 20-year outcomes of TC and surgical closure (SC) for typical…

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