Chronic Bronchiolitis in Adults
Fig. 3.1 Junctional area between the purely conductive airways and the respiratory portion of the lung. The terminal (nonrespiratory) bronchiole has a continuous cuboidal epithelium, whereas alveoli open off the…
Multiple Cystic Lung Diseases
Folliculin gene (FLCN)-associated syndrome Birt-Hogg-Dubé syndrome Familial spontaneous pneumothorax Lymphangioleiomyomatosis Sporadic Tuberous sclerosis complex associated Pulmonary Langerhans cell histiocytosis Lymphoid disorders Lymphoid interstitial pneumonia, idiopathic or associated with connective tissue…
Alveolar Hemorrhage
Histology Etiologies Pulmonary Capillaritis Granulomatosis with polyangitis Microscopic polyangitis Isolated pulmonary capillaritis Systemic lupus erythematosus Primary antiphospholipid antibody syndrome Other collagen vascular disorders/connective tissue diseases Henoch-Schönlein purpura Behçet Syndrome Goodpasture…
Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Syndrome): A Clinical and Therapeutic Approach
Parameter Chumbley et al. (1977) [35] Lanham et al. (1984) [36] Gaskin et al. (1991) [37]a Comarmond et al. (2012) [39] Abu-Shakra et al. (1994) [38] Guillevin et al. (1999)…
Interstitial Lung Disease in Systemic Sclerosis
Fig. 25.1 Cellular NSIP. The lung shows diffuse involvement of the alveolar interstitium by a mild chronic inflammatory infiltrate Fig. 25.2 Fibrotic NSIP. The lung shows diffuse involvement of the…
Pulmonary Manifestations of Hematological Malignancies: Focus on Pulmonary Chronic Graft-Versus Host Disease
Antibiotic chemotherapeutic agents Bleomycin, Mitomycin C Alkylating agents Busulfan, Cyclophosphamide, Chlorambucil, Melphalan, Ifosfamide, Procarbazine Antimetabolites Methotrexate, 6-mercaptopurine, Cytosine arabinoside, Fludarabine Nitrosamines Bischloroethyl nitrosourea (BCNU), Chloroethyl cyclohexyl nitrosourea (CCNU), Methyl-CCNU Tubulin-acting…
Pulmonary Hypertension in Orphan Lung Diseases
1. Pulmonary arterial hypertension 1.1 Idiopathic PAH 1.2 Heritable 1.2.1. BMPR2 1.2.2. ALK1, endoglin, SMAD9, CAV1, KCNK3 1.2.3 Unknown 1.3 Drug- and toxin-induced 1.4 Associated with 1.4.1. Connective tissue diseases…
Hepatopulmonary Syndrome
1. Presence of liver disease (a) Cirrhotic or non-cirrhotic portal hypertension 2. Intrapulmonary vascular dilatations (a) Positive transthoracic contrast/bubble echocardiogram (b) 99mTechnetium lung/brain perfusion scan 3. Hypoxemia (a) Seated room…
Pulmonary Involvement in Takayasu Arteritis and Behçet Disease
1. Age at disease onset <40 years Development of symptoms or findings related to Takayasu arteritis at age <40 years 2. Claudication of extremities Development and worsening of fatigue and…
Amyloidosis and the Respiratory Tract
Type Fibril protein precursor Clinical syndrome AA Serum amyloid A protein Reactive systemic amyloidosis associated with chronic inflammatory diseases AL Monoclonal immunoglobulin light chains Systemic amyloidosis associated with monoclonal plasma…
