Fig. 35.1 Pneumonic-type lung adenocarcinoma. (a) Computed tomography scan of a 66 year-old former smoker woman, who presented with progressive cough. Multiple bilateral alveolar condensation-like masses with irregular margins are…
Fig. 24.1 (a, b) Histopathological pattern of organizing pneumonia at surgical lung biopsy: buds of granulation tissue containing myofibroblasts and inflammatory cells embedded in a loose connective matrix, and filling…
Fig. 18.1 Chest CT scan of a patient with autoimmune PAP. Reticulations are superimposed on ground-glass opacities forming a “crazy paving” pattern with a geographic distribution: juxtaposition of healthy and…
Fig. 3.1 Junctional area between the purely conductive airways and the respiratory portion of the lung. The terminal (nonrespiratory) bronchiole has a continuous cuboidal epithelium, whereas alveoli open off the…
Folliculin gene (FLCN)-associated syndrome Birt-Hogg-Dubé syndrome Familial spontaneous pneumothorax Lymphangioleiomyomatosis Sporadic Tuberous sclerosis complex associated Pulmonary Langerhans cell histiocytosis Lymphoid disorders Lymphoid interstitial pneumonia, idiopathic or associated with connective tissue…
Histology Etiologies Pulmonary Capillaritis Granulomatosis with polyangitis Microscopic polyangitis Isolated pulmonary capillaritis Systemic lupus erythematosus Primary antiphospholipid antibody syndrome Other collagen vascular disorders/connective tissue diseases Henoch-Schönlein purpura Behçet Syndrome Goodpasture…
Parameter Chumbley et al. (1977) [35] Lanham et al. (1984) [36] Gaskin et al. (1991) [37]a Comarmond et al. (2012) [39] Abu-Shakra et al. (1994) [38] Guillevin et al. (1999)…
Fig. 25.1 Cellular NSIP. The lung shows diffuse involvement of the alveolar interstitium by a mild chronic inflammatory infiltrate Fig. 25.2 Fibrotic NSIP. The lung shows diffuse involvement of the…
Antibiotic chemotherapeutic agents Bleomycin, Mitomycin C Alkylating agents Busulfan, Cyclophosphamide, Chlorambucil, Melphalan, Ifosfamide, Procarbazine Antimetabolites Methotrexate, 6-mercaptopurine, Cytosine arabinoside, Fludarabine Nitrosamines Bischloroethyl nitrosourea (BCNU), Chloroethyl cyclohexyl nitrosourea (CCNU), Methyl-CCNU Tubulin-acting…
1. Pulmonary arterial hypertension 1.1 Idiopathic PAH 1.2 Heritable 1.2.1. BMPR2 1.2.2. ALK1, endoglin, SMAD9, CAV1, KCNK3 1.2.3 Unknown 1.3 Drug- and toxin-induced 1.4 Associated with 1.4.1. Connective tissue diseases…
