Study design for an emulated trial of a 2 arm, parallel, stratified, adaptive, RCT of CABG versus PCI in people requiring myocardial revascularization at high risk (High-Risk REVASC)

Jun 27, 2026 by in CARDIOLOGY Comments Off on Study design for an emulated trial of a 2 arm, parallel, stratified, adaptive, RCT of CABG versus PCI in people requiring myocardial revascularization at high risk (High-Risk REVASC)
ABSTRACT Aim This study aims to use routinely collected health data and trial emulation methodology to inform the design of a pragmatic randomized controlled trial (RCT) in people requiring multivessel…
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Admission rates for pediatric supraventricular tachycardia are affected by primary insurance payor: An analysis of the NEDS database

Jun 27, 2026 by in CARDIOLOGY Comments Off on Admission rates for pediatric supraventricular tachycardia are affected by primary insurance payor: An analysis of the NEDS database
Highlights • Publicly insured patients are more likely to be admitted/transferred for SVT. • This finding is more pronounced in older pediatric age groups. • Patients <1 year of age…
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Early outcomes of off-label transcatheter tricuspid valve repair/replacement in the STS/ACC TVT registry

Jun 27, 2026 by in CARDIOLOGY Comments Off on Early outcomes of off-label transcatheter tricuspid valve repair/replacement in the STS/ACC TVT registry
ABSTRACT Background Transcatheter tricuspid valve interventions (TTVI) have expanded with the recent FDA approval of both replacement transcatheter tricuspid valve replacement (TTVR) and edge-to-edge repair (T-TEER) devices. However, the volume…
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Primary percutaneous coronary intervention within the first hour: Insights from early-treated patients with ST-elevation myocardial infarction

Jun 27, 2026 by in CARDIOLOGY Comments Off on Primary percutaneous coronary intervention within the first hour: Insights from early-treated patients with ST-elevation myocardial infarction
Highlights • Performing primary percutaneous coronary intervention (PPCI) ≤60 minutes of randomization resulted in a significant reduction in the 30-day composite outcome of all-cause death, shock, heart failure, and reinfarction…
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Evidence supporting the role of longitudinal NT-proBNP assessment for risk stratification in adults with congenital heart disease

Jun 27, 2026 by in CARDIOLOGY Comments Off on Evidence supporting the role of longitudinal NT-proBNP assessment for risk stratification in adults with congenital heart disease
ABSTRACT Background The role of N-terminal pro-B-type natriuretic peptide (NT-proBNP) risk stratification in adults with congenital heart disease (CHD) is not well defined because of paucity of data. The purpose…
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Low levels of atherogenic lipoproteins and incident atherosclerotic cardiovascular disease: A pooled cohort primary prevention study

Jun 27, 2026 by in CARDIOLOGY Comments Off on Low levels of atherogenic lipoproteins and incident atherosclerotic cardiovascular disease: A pooled cohort primary prevention study
Highlights • ASCVD-free adults with LDL-C < 70 vs 70 to 99 mg/dL had similar long-term ASCVD risk. • Adults with LDL-C ≥ 130 mg/dL had higher long-term ASCVD risk….
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Reperfusion strategies for acute pulmonary embolism: Design and rationale of RECONNECT-PE—A living systematic review and meta-analysis

Jun 27, 2026 by in CARDIOLOGY Comments Off on Reperfusion strategies for acute pulmonary embolism: Design and rationale of RECONNECT-PE—A living systematic review and meta-analysis
Highlights • Living review to assess reperfusion strategies for severe pulmonary embolism. • Synthesizes ongoing and future RCTs using predefined, rigorous methods. • Compares efficacy and safety of systemic lysis,…
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Integrated care management for older multimorbid patients with atrial fibrillation: Rationale, design and baseline characteristics for the atrial fibrillation integrated approach in frail, multimorbid and polymedicated older people (AFFIRMO) trial

Jun 27, 2026 by in CARDIOLOGY Comments Off on Integrated care management for older multimorbid patients with atrial fibrillation: Rationale, design and baseline characteristics for the atrial fibrillation integrated approach in frail, multimorbid and polymedicated older people (AFFIRMO) trial
ABSTRACT Introduction Atrial fibrillation (AF) is the most common arrhythmia in older people, with an increasing prevalence of various geriatric conditions, such as multimorbidity, and frailty. A contemporary integrated approach…
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