Chronic altitude illness
24 Chronic altitude illness Introduction Chronic mountain sickness Historical Epidemiology of CMS Clinical aspects of CMS Hemodynamics Prevention Treatment Pathophysiology of CMS with normal lungs Excessive erythrocytosis with lung disease…
Genetics and genomics of exposure to high altitude
6 Genetics and genomics of exposure to high altitude Introduction History Variation at the molecular level Omics analysis Candidate genes Hypoxia-inducible factors Description of hypoxia-inducible factors HIF responses to hypoxia…
Race is not a risk factor: Reframing discourse on racial health inequities in CVD prevention
We respectfully submit this letter in response to the March 2021 state-of-the-art review article “Ten things to know about ten cardiovascular disease risk factors” . Although the article effectively summarizes…
Low-Density Lipoprotein Cholesterol Treatment Rates in High Risk Patients: More Disappointment Despite Ever More Refined Evidence-Based Guidelines.
American physicians are now treating dyslipidemia according to a fifth iteration of national guidelines for the use of lipid-lowering therapies . These guidelines are developed with considerable care and deliberation…
Geographic variations in lipid-lowering therapy utilization, LDL-C levels, and proportion retrospectively meeting the ACC/AHA very high-risk criteria in a real-world population of patients with major atherosclerotic cardiovascular disease events in the United States
Abstract Objective We assessed national- and state-level geographic variations among patients with a history of ≥1 major atherosclerotic cardiovascular disease (ASCVD) event in: (1) the proportion of patients with retrospectively…
Optimizing sodium-glucose co-transporter 2 inhibitor use in patients with heart failure with reduced ejection fraction: A collaborative clinical practice statement
Highlights • HFrEF is a debilitating disease with substantial morbidity, mortality, and costs. • SGLT2i reduce adverse cardiovascular (including HF) and renal events. • SGLT2i have ushered in a new…
