(1) The Molecular Cardiology and Neuromuscular Institute, Highland Park, NJ, USA Abstract Cardiac mitochondria are complex highly organized cellular organelles, which play central roles not only in energy homeostasis…
(1) The Molecular Cardiology and Neuromuscular Institute, Highland Park, NJ, USA Abstract The ability of thyroid hormone to regulate energy utilization was first recognized more than 100 years ago…
(1) The Molecular Cardiology and Neuromuscular Institute, Highland Park, NJ, USA Abstract Heart failure is common in patients with diabetes, even in the absence of coronary artery disease or…
(1) The Molecular Cardiology and Neuromuscular Institute, Highland Park, NJ, USA Abstract Under pathophysiological conditions, reactive oxygen species (ROS) levels may increase and cause cell damage and dysfunction targeting…
(1) The Molecular Cardiology and Neuromuscular Institute, Highland Park, NJ, USA Abstract Ischemia and postischemic reperfusion cause a wide array of functional and structural alterations of mitochondria. Although mitochondrial…
(1) The Molecular Cardiology and Neuromuscular Institute, Highland Park, NJ, USA Abstract The two opposing highly regulated processes, division (fission) and fusion, determine cell-type-specific mitochondrial morphology, intracellular distribution, and…
(1) The Molecular Cardiology and Neuromuscular Institute, Highland Park, NJ, USA Abstract Ventricular dysrhythmias represent the most predominant etiology of sudden cardiac death throughout the world. However, the mechanisms…
(1) The Molecular Cardiology and Neuromuscular Institute, Highland Park, NJ, USA Abstract Aging is associated with progressive impairment of a variety of vital functions, resulting in an increased vulnerability…
(1) The Molecular Cardiology and Neuromuscular Institute, Highland Park, NJ, USA Abstract Mitochondria are both sources and targets of reactive oxygen species, and there is increasing evidence that mitochondrial…
(1) The Molecular Cardiology and Neuromuscular Institute, Highland Park, NJ, USA Abstract In this introductory chapter to Mitochondria Role in Cardiovascular Diseases, we will discuss those primary defects in…
