Contemporary Surgical Management of Hypertrophic Cardiomyopathy, the Need for More Myectomy Surgeons and Disease-Specific Centers, and the Tufts Initiative

Dec 5, 2016 by in CARDIOLOGY Comments Off on Contemporary Surgical Management of Hypertrophic Cardiomyopathy, the Need for More Myectomy Surgeons and Disease-Specific Centers, and the Tufts Initiative

Treatment strategies for symptomatic patients with obstructive hypertrophic cardiomyopathy (HC) represent an important component of the overall management armamentarium for this complex genetic disease, and have generated considerable debate in…

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The Heart Team Approach to Coronary Revascularization—Have We Crossed the Lines of Evidence-Based Medicine?

Dec 5, 2016 by in CARDIOLOGY Comments Off on The Heart Team Approach to Coronary Revascularization—Have We Crossed the Lines of Evidence-Based Medicine?

Evidence-based medicine demands considerable time and decision-making skills to navigate through the proliferating data. A hierarchical “pyramid of evidence” has been formulated to help categorize data quality. The hierarchical data…

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Effect of Extended-Release Niacin on Serum Lipids and on Endothelial Function in Adults With Sickle Cell Anemia and Low High-Density Lipoprotein Cholesterol Levels

Dec 5, 2016 by in CARDIOLOGY Comments Off on Effect of Extended-Release Niacin on Serum Lipids and on Endothelial Function in Adults With Sickle Cell Anemia and Low High-Density Lipoprotein Cholesterol Levels

Through bound apolipoprotein A-I (apoA-I), high-density lipoprotein cholesterol (HDL-C) activates endothelial nitric oxide synthase, inducing vasodilation. Because patients with sickle cell disease (SCD) have low apoA-I and endothelial dysfunction, we…

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Relation of Preoperative Serum Albumin Levels to Survival in Patients Undergoing Left Ventricular Assist Device Implantation

Dec 5, 2016 by in CARDIOLOGY Comments Off on Relation of Preoperative Serum Albumin Levels to Survival in Patients Undergoing Left Ventricular Assist Device Implantation

Hypoalbuminemia has been recognized as a prognostic indicator in patients with heart failure. We aimed to investigate the association of hypoalbuminemia with postoperative mortality in patients undergoing left ventricular assist…

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Usefulness of High-Dose Intravenous Human Immunoglobulins Treatment for Refractory Recurrent Pericarditis

Dec 5, 2016 by in CARDIOLOGY Comments Off on Usefulness of High-Dose Intravenous Human Immunoglobulins Treatment for Refractory Recurrent Pericarditis

The management of refractory recurrent pericarditis is challenging. Previous clinical reports have noted a beneficial effect of high-dose intravenous human immunoglobulins (IvIgs) in isolated and systemic inflammatory disease-related forms. In…

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