Author’s Reply
In the control group of the Moderate Pulmonary Embolism Treated With Thrombolysis (MOPETT) trial, the mean pulmonary artery systolic pressure (PASP) decreased from 51 to 43 mm Hg within 28 months,…
A Predictive Risk Model for Transcatheter Aortic Valve Procedures. An Extraordinary Tool but a Formidable Challenge
Durand et al are to be commended for their interesting study on assessing the performance of the European System for Cardiac Operative Risk Evaluation (EuroSCORE) II for predicting 30-day mortality in…
“Thinking Outside the Box” on Takotsubo Syndrome
Reading the rapidly expanding data on Takotsubo syndrome (TTS), one can sense that some stagnation has been creeping into the field. All the case studies and review articles appear identical…
Throw the Stethoscope Away: A Historical Essay
Am I going deaf, or are hearts not as noisy as they used to be? I’ve had my hearing tested, just some high-frequency loss (probably from that Edgar Winter concert)….
Unusually High Incidence of Pulmonary Hypertension in MOPETT Trial
In a report from the recent Moderate Pulmonary Embolism Treated With Thrombolysis (MOPETT) trial, the investigators described the efficacy of low-dose tissue plasminogen activator in reducing the incidence of pulmonary arterial…
Dramatically Different Phenotypic Expressions of Hypertrophic Cardiomyopathy in Male Cousins Undergoing Cardiac Transplantation With Identical Disease-Causing Gene Mutation
Described herein are certain findings in 2 male cousins who underwent cardiac transplantation for severe heart failure (HF), one of the diastolic type (ejection fraction ≈65%), and one of the…
Good Books in Cardiovascular Disease Appearing in 2012 and Early 2013
Major Textbooks 1. Allen HD, Driscoll DJ, Shaddy RE, Feltes TF. Moss and Adams’ Heart Disease in Infants, Children, and Adolescents: Including the Fetus and Young Adults . 8th ed….
Association of Cardiac Troponin I With Disease Severity and Outcomes in Patients With Pulmonary Hypertension
Previous studies have identified cardiac troponin I (cTnI) as an important marker in pulmonary hypertension (PH) prognosis. However, traditional assays are limited by poor sensitivity, even among patients at high…
Relation Between Serum Thrombospondin-2 and Cardiovascular Mortality in Older Men Screened for Abdominal Aortic Aneurysm
Thrombospondin-1 and -2 (TSP-1 and -2) have been implicated in the regulation of angiogenesis, thrombosis, and inflammation, which are believed to be critical in the pathogenesis of cardiovascular events. The…
Dose Effect of Cardiorespiratory Exercise on Metabolic Syndrome in Postmenopausal Women
As an ancillary report to a large National Institutes of Health (NIH)–funded trial, we examined the effects of 6 months of exercise training at 50%, 100%, and 150% of the…
