Anderson-Fabry disease is a lysosomal storage disorder caused by α-galactosidase defects and progressive intracellular accumulation of globotriaosylceramide. The disease can be specifically treated with enzyme replacement therapy. Hemizygous men and…
Landgraf et al reported “differences” between 2 blood pressure values measured simultaneously in a group of subjects. Their concept is that there is a valid way to compare auscultatory estimates…
The article by the group in Toronto concludes that an increase in the ratio of systolic to diastolic intervals in patients with pulmonary arterial hypertension predicts poorer survival. That ratio…
In their report, Turer and Hill reviewed the pathogenesis of myocardial ischemia-reperfusion injury and rationale for therapy. They discussed the role of mitochondria in reactive oxygen species production. We would…
The cardiac effects imposed by the novel H1N1 influenza strain have not been elucidated until now. Electrocardiographic (ECG) abnormalities were evaluated in a series of 50 patients with confirmed novel…
I was intrigued by the report of Morin et al in the June 15 issue of The American Journal of Cardiology on the differences in the frequency of T-wave inversion…
I read with interest the report by Chung et al, who presented a case series of predominantly Caucasian elderly Australians with apical hypertrophic cardiomyopathy (HC). Almost 3 decades ago, Steingo…
We sought to compare the angiographic findings and mortality in patients with non–ST-segment elevation (NSTEMI) versus ST-segment elevation myocardial infarction (STEMI) undergoing early invasive intervention. Of 11,872 patients enrolled in…
Adults with Down syndrome (DS) residing in large institutional settings possess low levels of atherosclerosis. The purpose of this study was to determine whether community-residing adults with DS possess less…
Left ventricular (LV) diastolic filling is characterized by the formation of intraventricular rotational bodies of fluid (termed “vortex rings”) that optimize the efficiency of LV ejection. The aim of the…
