Preinvasive Lesions
Preinvasive Lesions Keith M. Kerr FRCPath Three recognized preinvasive lesions are precursors of invasive tumors in the bronchial tree and lung: squamous dysplasia and carcinoma in situ (SD/CIS) of the…
GENERAL
Non–Small Cell Carcinomas
Non–Small Cell Carcinomas Kun Y. Kwon MD Keith M. Kerr FRCPath Jae Y. Ro MD Histologically, and largely through an imperative of patient management, lung carcinomas are divided into two…
Neuroendocrine Tumors
Neuroendocrine Tumors Keith M. Kerr FRCPath Kun Y. Kwon MD Jae Y. Ro MD The two separate categories of neuroendocrine tumors in the World Health Organization (WHO) classification of lung…
Artifacts and Nonspecific Changes
Artifacts and Nonspecific Changes Timothy C. Allen MD, JD Philip T. Cagle MD The pathologist should be aware of the artifacts and nonspecific changes that may be seen in a…
Overview of Transbronchial and Endobronchial Biopsies
Overview of Transbronchial and Endobronchial Biopsies Timothy C. Allen MD, JD Philip T. Cagle MD Transbronchial and endobronchial biopsies are procedures of limited invasiveness performed by bronchoscopy, typically aided by…
The Adolescent and Adult with Congenital Heart Disease
The Adolescent and Adult with Congenital Heart Disease Ali N. Zaidi Curt J. Daniels Prevalence of Adult Congenital Heart Disease (ACHD) Most patients born with moderate or severe forms of…
Pediatric Pulmonary Hypertension
Pediatric Pulmonary Hypertension Dunbar Ivy Pulmonary hypertension (PH) is an important cause of morbidity and mortality in pediatric patients (1,2,3). Advances in understanding the pathobiology of pulmonary arterial hypertension (PAH)…
Pathophysiology of Pulmonary Hypertension
Pathophysiology of Pulmonary Hypertension Marlene Rabinovitch Rachel K. Hopper Introduction This chapter addresses the pathophysiologic mechanisms leading to pulmonary hypertension associated with congenital heart defects and other disease-related or idiopathic…
Safety and Quality in the Heart Center
Safety and Quality in the Heart Center Anthony Y. Lee Tom Taghon Richard McClead Wallace Crandall Terrance Davis Richard J. Brilli Introduction Much Quality, Safety, and Continuous Quality Improvement (QI)…
Pericardial Diseases
Pericardial Diseases Jonathan N. Johnson Frank Cetta Anatomy and Physiology The pericardium is comprised of two principal layers, the visceral pericardium and the parietal pericardium. The visceral pericardium, or epicardium,…
