Abstract As neonatal intensive care has evolved over the past decades, the clinical decision to treat preterm infants with persistent patent ductus arteriosus (PDA) with surgical ligation has become increasingly…
Abstract In the absence of outcome-based evidence to guide circulatory support in the newborn, a logical approach is one that uses individual- or precision-based therapy. That is, one should try…
Abstract The dynamic physiologic changes that take place in the cardiovascular system of the preterm and term neonate during the transitional period are poorly characterized, especially when it comes to…
Abstract The goal of predictive monitoring is to predict or detect adverse events far enough in advance of conventional detection methods to allow for earlier treatment and improved outcomes. The…
Abstract Near-infrared spectroscopy (NIRS) can monitor regional cerebral oxygen saturation (rScO 2 ), mostly representing oxygen supply to the brain. The ratio between rScO 2 and systemic oxygen saturation (SaO…
Abstract Light-based approaches to the assessment of a tissue’s oxygen status are attractive to the clinician because they provide the possibility of continuous noninvasive measurements. For example, pulse oximetry, which…
Abstract Appropriate monitoring of the cardiovascular system and thus the treatment of critically ill neonates with cardiovascular compromise hinges on the ability to monitor at least two of the three…
Abstract Complex forms of congenital heart disease (CHD) often require early and or emergent medical, surgical, or catheterization–based interventions in the first days to weeks of postnatal life. CHD lesions…
Abstract Considerable advances in catheter-based therapies have recently allowed interventional cardiac catheterization to play a major role in treating infants with congenital heart disease (CHD). In the neonatal period, a…
Abstract Although a patent ductus arteriosus (PDA) can easily be visualized using ultrasound, the challenge is in differentiating a hemodynamically significant and potentially harmful ductus arteriosus from one which does…
