Genetic Susceptibility to Lung Cancer
Genetic Susceptibility to Lung Cancer Christopher I. Amos Joan E. Bailey-Wilson Lung cancer is the most common cause of cancer death in the United States1 with 162,000 deaths estimated for…
Nontobacco-Related Lung Carcinogenesis
Nontobacco-Related Lung Carcinogenesis Tze-Ming Benson Chen Ware G. Kuschner Lung cancer is estimated to cause 17,000 to 26,000 deaths among nonsmokers annually in the United States.1 Secondhand smoke exposure explains…
The Tobacco Epidemic
The Tobacco Epidemic Carolyn Dresler Tobacco has a fascinating history. Tobacco is native only to the Americas and its scientific names include Nicotiana rustica and Nicotiana tabacum.1 Tobacco was first…
The Etiology and Epidemiology of Lung Cancer
The Etiology and Epidemiology of Lung Cancer David Schottenfeld Lung cancer is the leading cause of cancer mortality in men and women in the United States, accounting for an estimated…
Thoracic Aortic Atherosclerosis
Thoracic Aortic Atherosclerosis Allen P. Burke, M.D. Epidemiology and Risk Factors In developed countries, atherosclerosis occurs in virtually every aorta, beginning in the second to third decades, with more rapid…
Noninflammatory Thoracic Aortic Aneurysms and Dissections
Noninflammatory Thoracic Aortic Aneurysms and Dissections Allen P. Burke, M.D. Joseph J. Maleszewski, M.D. Terminology The term aneurysm refers to a dilatation of a structure beyond its expected borders. Thus,…
Pericardial Metastases
Pericardial Metastases Joseph J. Maleszewski, M.D. Allen P. Burke, M.D. Incidence and Histologic Types About 10% of all patients with advanced-stage cancer develop cardiac metastasis, with the majority (about 75%)…
Pericardial Mesothelioma
Pericardial Mesothelioma Allen P. Burke, M.D. Terminology Malignant mesotheliomas of the pericardium are malignant tumors derived from pericardial mesothelial cells and partly or completely encase the heart, with an absent…
Pericardial Cysts and Cystic Lesions
Pericardial Cysts and Cystic Lesions Allen P. Burke, M.D. Mesothelial (Pericardial) Cysts Mesothelial cysts account for ˜20% to 30% of mediastinal cysts. Bronchogenic cysts are more common, but are usually…
