Fig. 9.1 Mesenchymal progenitors support epithelial regeneration via the release of growth factors like FGF-10 which promote the proliferation of epithelial stem/progenitor cells . The differentiation of mesenchymal progenitors cells…
Fig. 7.1 Stem cells of the distal bronchiolar airways. (a) Murine distal airways are primarily composed of ciliated, secretory (Club), and neuroendocrine cells. Lineage tracing studies using genetically modified mouse…
104. Chamoto K et al (2013) Migration of CD11b+ accessory cells during murine lung regeneration. Stem Cell Res 10(3):267–277PubMedCentralPubMed 105. Sun Z et al (2014) Inhibition of Wnt/beta-catenin signaling promotes…
Fig. 2.1 Epithelial-mesenchymal-endothelial-nerve-matrix crosstalk in early mouse lung . This concept figure diagrams many of the known interactions between these compartments in lung morphogenesis. In the proximal lung, Sox9-positive mesenchymal…
© Springer International Publishing Switzerland 2015Ivan Bertoncello (ed.)Stem Cells in the LungStem Cell Biology and Regenerative Medicine10.1007/978-3-319-21082-7_3 3. Lung Vasculogenesis and Angiogenesis Bernard Thébaud1 and Mervin C. Yoder2 (1) Division of Neonatology, Department of Pediatrics, Sinclair Centre…
Fig. 6.1 Schematic representation of our current understanding of stem and progenitor cells responsible for maintenance and repair of the proximal airway surface epithelium and submucosal glands. LRC label retaining…
Fig. 7.1. Patient presenting with a traumatic pneumothorax after blunt trauma to the chest. Black arrows denote the outline of the collapsed lung. Massive air leak suggests injury to major…
Fig. 8.1. Esophageal anatomy. Used with permission from the McGill University Health Centre Patient Education Office. Table 8.1. Vasculature, lymphatics, and innervation of the esophagus. Cervical esophagus Thoracic esophagus…
Fig. 9.1. Natural history of Barrett’s oesophagus. Risk factors: Chronic gastroesophageal reflux disease (GERD; worse with nocturnal symptoms), risk factors for GERD (age, male, obesity, caffeine, alcohol, tobacco and spicy,…
Lung cancer TNM staging Primary tumour (T) T1 Tumour ≤3 cm diameter, surrounded by lung or visceral pleura, without invasion more proximal than lobar bronchus T1a Tumour ≤2 cm in…
