Asthma in Childhood: Special Considerations

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Fig. 14.1 Overlap between difficult-to-control and severe asthma 14.2.1 Asthma Masqueraders Asthma mimics are common and typically poorly or unresponsive to conventional asthma management and therapies. The differential diagnosis for…

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Asthma Clinic: Putting It All Together

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Purpose of a high-risk clinic Address diagnostic uncertainties Recognize and manage factors that make asthma “difficult to treat”  Persistent triggers  Suboptimal adherence and inhaler technique  Uncontrolled comorbidities Optimize self-management skills…

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in Severe Asthma

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Fig. 7.1 The five adult clinical cluster phenotypes from the Severe Asthma Research Program (SARP) with the predominant clinical characteristics. (Reprinted with permission of the American Thoracic Society. Copyright ©…

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and Management of Work-Related Asthma

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Most common agents for occupational asthma Workers at risk of exposure Isocyanates Rigid or flexible polyurethane foam makers, polyurethane foam insulation installers, urethane spray painters, users of adhesives Flour Bakers,…

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Considerations in Management of Allergic Asthma

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Fig. 9.1 Induction of TH2 cells . TSLP, IL-25, and IL-33 produced by respiratory epithelium on exposure to respiratory allergens, pollutants, or viruses promote the induction of allergen-specific TH2 cells….

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Asthma: Unmet Needs and Future Directions

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!DOCTYPE html> © Springer Nature Switzerland AG 2020S. Khurana, F. Holguin (eds.)Difficult To Treat AsthmaRespiratory Medicinehttps://doi.org/10.1007/978-3-030-20812-7_16 16. Difficult Asthma: Unmet Needs and Future Directions Shu-Yi Liao1  , Amir A. Zeki1   and Nizar Jarjour2   (1) Division of Pulmonary, Critical…

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Asthma in Pregnancy: Special Considerations

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Parameter Changes in pregnancy Respiratory rate Unchanged Minute ventilation Increases by 30–50% Tidal volume (Vt) Increases by 40% Oxygen consumption Increases by 20% Forced expiratory volume in 1 s (FEV1) Unchanged…

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Considerations in Management of Non-eosinophilic Asthma

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Fig. 11.1 Practical therapeutic approach to non-eosinophilic asthma. (LAMA Long-acting antimuscarinic antagonist, LABA Long-acting beta agonists, SABA Short-acting beta agonists, TSLP Thymic stromal lymphopoietin) The first step is to confirm…

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