Systems of Health Care
A system is an interconnected set of elements organized to achieve a function or purpose. A system of care is an interconnected care delivery system, usually in a geographically contiguous…
GENERAL
Pharmacogenetics
Interindividual variability of drug response has been well documented. In addition to drug-drug and drug-environment interactions, genetic factors have emerged as contributors to variability in response to several cardiovascular medications….
Device Development for Cardiovascular Therapeutics: Concepts and Regulatory Implications
Overview Over the past 50 years, new medical devices and related innovations have contributed greatly to the decrease in deaths from cardiovascular causes. Indeed, cardiovascular device development has advanced dramatically…
New Drug Development
Cardiovascular medicine has been in the vanguard of new therapeutic development since 1955, when President Dwight Eisenhower’s myocardial infarction (MI) in office captured worldwide attention. Many forces contribute to this…
Legal Aspects of Endobronchial and Transbronchial Biopsy
Legal Aspects of Endobronchial and Transbronchial Biopsy Timothy C. Allen MD, JD Clinicians’ medicolegal concerns about transbronchial and endobronchial biopsies generally arise from medical complications such as severe pneumothorax and…
Tracheobronchial Biopsy for Primary Ciliary Dyskinesia
Tracheobronchial Biopsy for Primary Ciliary Dyskinesia Megan K. Dishop MD Primary ciliary dyskinesia (PCD) is a rare disorder of immotile or abnormally motile cilia resulting in chronic recurrent respiratory infection,…
Bronchial Masses in the Pediatric Population
Bronchial Masses in the Pediatric Population Megan K. Dishop MD Endobronchial biopsy is occasionally performed for diagnosis and/or excision of obstructive tracheal and endobronchial masses. Most bronchial lesions in children…
Role of Transbronchial and Endobronchial Biopsies in Children
Role of Transbronchial and Endobronchial Biopsies in Children Megan K. Dishop MD Transbronchial and endobronchial biopsy have been performed in children and adolescents since the 1980s, with technical advances since…
Nonneoplastic Large Airways Pathology
Nonneoplastic Large Airways Pathology Timothy C. Allen MD, JD Jaishree Jagirdar MD Keith M. Kerr FRCPath Endobronchial and transbronchial biopsy are used to diagnose neoplasms and infections involving the large…
Other Transplant Associated Pathology
Other Transplant Associated Pathology Anna Sienko MD Philip T. Cagle MD In addition to acute rejection, transbronchial biopsy is typically used for lung transplant recipients for diagnosis of opportunistic infections…
