Assessment of the gradient gap after TAVR with balloon and self-expandable valves: Analysis of a large patient cohort

Jun 27, 2026 by in CARDIOLOGY Comments Off on Assessment of the gradient gap after TAVR with balloon and self-expandable valves: Analysis of a large patient cohort
Highlights • Echocardiography systematically overestimates post-TAVR gradients compared with invasive measurements, particularly with balloon-expandable valves. • Gradient discrepancy (Echo-Invasive) was not linked to increased 30-day or 1-year mortality. • Female…
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Trial event rate assumption and noninferiority margin in comparative trials of aortic valve replacement

Jun 27, 2026 by in CARDIOLOGY Comments Off on Trial event rate assumption and noninferiority margin in comparative trials of aortic valve replacement
ABSTRACT This letter evaluates whether overestimation of control event rates and the use of absolute noninferiority margins influenced conclusions of randomized trials comparing transcatheter and surgical aortic valve replacement. By…
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Outcomes of implantable cardioverter-defibrillator implantation in adults with congenitally corrected transposition of great arteries

Jun 27, 2026 by in CARDIOLOGY Comments Off on Outcomes of implantable cardioverter-defibrillator implantation in adults with congenitally corrected transposition of great arteries
ABSTRACT Background Ventricular arrhythmias and sudden cardiac death (SCD) are common in adults with congenitally corrected transposition of great arteries (cc-TGA). The purpose of this study was to describe the…
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Enhancing invasive coronary function testing: Multivessel assessment of coronary microvascular dysfunction in patients with angina and no obstructive coronary artery disease (ANOCA)

Jun 27, 2026 by in CARDIOLOGY Comments Off on Enhancing invasive coronary function testing: Multivessel assessment of coronary microvascular dysfunction in patients with angina and no obstructive coronary artery disease (ANOCA)
ABSTRACT Background Invasive coronary function testing (ICFT) is the gold standard for diagnosing coronary microvascular dysfunction (CMD) and is predominantly performed in the left anterior descending coronary artery (LAD). However,…
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Adults with repaired systemic biventricular congenital heart disease with a systemic left ventricle and heart failure with reduce ejection fraction

Jun 27, 2026 by in CARDIOLOGY Comments Off on Adults with repaired systemic biventricular congenital heart disease with a systemic left ventricle and heart failure with reduce ejection fraction
ABSTRACT Background Results of observational studies assessing clinical benefits of guideline-directed medical therapy (GDMT) for heart failure (HF) in adults with congenital heart disease are conflicting. This is because these…
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Operator radiation exposure comparing left-radial artery and right-radial artery approaches: A systematic review and meta-analysis

Jun 27, 2026 by in CARDIOLOGY Comments Off on Operator radiation exposure comparing left-radial artery and right-radial artery approaches: A systematic review and meta-analysis
Highlights • Operator radiation exposure (ORE) can have adverse long-term effects. • First meta-analysis to compare operator radiation exposure when using LRA vs RRA. • Cumulative ORE lower for the…
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