Design and rational of the the PRACTICAL-HERO trial: A randomized trial of higher and lower doses of heparin vs placebo for elective diagnostic coronary angiography

Jun 27, 2026 by in CARDIOLOGY Comments Off on Design and rational of the the PRACTICAL-HERO trial: A randomized trial of higher and lower doses of heparin vs placebo for elective diagnostic coronary angiography
Highlights • PRACTICAL HERO: RCT in patients undergoing diagnostic cardiac catheterization. • Evaluates heparin vs placebo for preventing radial artery occlusion. • Compares high-dose vs low-dose unfractionated heparin strategies. •…
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Optimal antiplatelet strategy in patients with advanced chronic kidney disease undergoing drug-eluting stent implantation: Design and rationale of the randomized ADAPT-CKD trial

Jun 27, 2026 by in CARDIOLOGY Comments Off on Optimal antiplatelet strategy in patients with advanced chronic kidney disease undergoing drug-eluting stent implantation: Design and rationale of the randomized ADAPT-CKD trial
ABSTRACT Background Although shortened dual antiplatelet therapy (DAPT) strategies have demonstrated favorable outcomes in the general percutaneous coronary intervention (PCI) population, patients with advanced chronic kidney disease (CKD) have been…
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Viewpoint on exception from informed consent: Enabling infarct-related shock trials in the U.S.

Jun 27, 2026 by in CARDIOLOGY Comments Off on Viewpoint on exception from informed consent: Enabling infarct-related shock trials in the U.S.
Abbreviations AMI: acute myocardial infarction; CS: cardiogenic shock; EFIC: exception from informed consent; LAR: legally authorized representative Acute myocardial infarction (AMI), cardiogenic shock (CS), and other cardiac emergencies have high…
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American Heart Association cardiovascular health metrics and cancer outcomes: A systematic review and meta-analysis

Jun 27, 2026 by in CARDIOLOGY Comments Off on American Heart Association cardiovascular health metrics and cancer outcomes: A systematic review and meta-analysis
Highlights • Higher American Heart Association (AHA) cardiovascular health (CVH) scores are associated with lower overall cancer incidence and mortality in meta-analysis. • Moderate and high CVH scores reduce overall…
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Impact of total stent length on long-term outcomes with different newer-generation drug-eluting stent designs in ST-segment elevation myocardial infarction: A subgroup analysis from the BIOSTEMI ES randomized trial

Jun 27, 2026 by in CARDIOLOGY Comments Off on Impact of total stent length on long-term outcomes with different newer-generation drug-eluting stent designs in ST-segment elevation myocardial infarction: A subgroup analysis from the BIOSTEMI ES randomized trial
Highlights • A TSL >40 mm is associated with an increased risk of patient-oriented, but not device-related, clinical outcomes at 5 years following primary PCI with newer-generation DES. • Contemporary…
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Comparative validation of risk scores for in-hospital complications following chronic total occlusion percutaneous coronary intervention

Jun 27, 2026 by in CARDIOLOGY Comments Off on Comparative validation of risk scores for in-hospital complications following chronic total occlusion percutaneous coronary intervention
Highlights • Head-to-head external validation of BMC2 and PROGRESS-CTO scores in CTO-PCI. • BMC2 showed excellent discrimination for in-hospital mortality in CTO-PCI. • PROGRESS-CTO demonstrated moderate accuracy for procedure-related complications….
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Characterization of biomarker profiles in patients with coronary artery disease: A prospective coronary computed tomography angiography study

Jun 27, 2026 by in CARDIOLOGY Comments Off on Characterization of biomarker profiles in patients with coronary artery disease: A prospective coronary computed tomography angiography study
HIGHLIGHTS • Patients with different stages of coronary artery disease exhibit significant differences in novel biomarkers. • Lp(a) appears to play a key role in early plaque development in patients…
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Systemic inflammation, myocardial fibrosis, and subclinical cardiovascular disease in people living with HIV

Jun 27, 2026 by in CARDIOLOGY Comments Off on Systemic inflammation, myocardial fibrosis, and subclinical cardiovascular disease in people living with HIV
ABSTRACT Background People living with HIV experience accelerated aging, increasing their risk of age-related diseases. Chronic inflammation may play an important role in premature vascular aging and myocardial fibrosis, leading…
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