Pegcetacoplan Treatment for Geographic Atrophy in Age-Related Macular Degeneration Over 36 Months: Data From OAKS, DERBY, and GALE

Jul 26, 2025 by in CARDIOLOGY Comments Off on Pegcetacoplan Treatment for Geographic Atrophy in Age-Related Macular Degeneration Over 36 Months: Data From OAKS, DERBY, and GALE

HIGHLIGHTS • Pegcetacoplan demonstrated increasing efficacy over time through 36 months. • Pegcetacoplan is the first GA treatment to show benefit in prespecified functional analyses. • Safety outcomes in the…

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Efficacy and Safety of Polypropylene Scleral Suture Fixation of Intraocular Lens in Pediatric Nontraumatic Ectopia Lentis: A Real-World Study

Jul 26, 2025 by in CARDIOLOGY Comments Off on Efficacy and Safety of Polypropylene Scleral Suture Fixation of Intraocular Lens in Pediatric Nontraumatic Ectopia Lentis: A Real-World Study

HIGHLIGHTS • The study focuses on the efficacy and safety of scleral-suture fixation of intraocular lens (SFIOL) in children with nontraumatic ectopia lentis (EL) in a real-world setting. • SFIOL…

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Primary Merkel cell carcinoma of the eyelid

Jul 26, 2025 by in CARDIOLOGY Comments Off on Primary Merkel cell carcinoma of the eyelid

A 70-year-old woman presented to the ophthalmology department with a two-month history of a progressively enlarging mass on her left upper eyelid. She denied visual impairment, ocular redness, or pain….

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Ocular Adverse Events Associated with Pegcetacoplan and Avacincaptad Pegol for Geographic Atrophy: A Population-Based Pharmacovigilance Study

Jul 26, 2025 by in CARDIOLOGY Comments Off on Ocular Adverse Events Associated with Pegcetacoplan and Avacincaptad Pegol for Geographic Atrophy: A Population-Based Pharmacovigilance Study

Highlights • Pegcetacoplan was linked to more adverse events than avacincaptad pegol based on FAERS. • Pegcetacoplan’s safety profile aligns with early clinical trial findings. • Avacincaptad pegol was linked…

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Reply to Comment on: “Epithelial Mapping Efficacy for Subclinical Keratoconus Identification”

Jul 26, 2025 by in CARDIOLOGY Comments Off on Reply to Comment on: “Epithelial Mapping Efficacy for Subclinical Keratoconus Identification”

We appreciate the opportunity to further clarify details from our recent article “Epithelial Mapping Efficacy for Subclinical Keratoconus Identification.” Toprak’s comments regarding our the subclinical keratoconus definition that we used…

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Clinical Characteristics of Patients With Less Common Causes of Leber Congenital Amaurosis/Early-Onset Severe Retinal Dystrophy

Jul 26, 2025 by in CARDIOLOGY Comments Off on Clinical Characteristics of Patients With Less Common Causes of Leber Congenital Amaurosis/Early-Onset Severe Retinal Dystrophy

Purpose To analyze the clinical characteristics, natural history, and genetics of Leber congenital amaurosis (LCA) early-onset severe retinal dystrophy (EOSRD) associated with uncommon genes. Design Single tertiary referral center, retrospective…

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Outcomes of Penetrating Keratoplasty Versus Lamellar Endothelial Keratoplasty in Iridocorneal Endothelial Syndrome: A Systematic Review and Meta-Analysis

Jul 26, 2025 by in CARDIOLOGY Comments Off on Outcomes of Penetrating Keratoplasty Versus Lamellar Endothelial Keratoplasty in Iridocorneal Endothelial Syndrome: A Systematic Review and Meta-Analysis

HIGHLIGHTS • PK may provide better graft survival compared to DSEK and DMEK. • Visual acuity improvements were comparable after PK, DSEK and DMEK. • Glaucoma surgery performed appear to…

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Natural History of Microperimetry and Optical Coherence Tomography in USH2A-Retinopathy: A Structure-Function Association Study

Jul 26, 2025 by in CARDIOLOGY Comments Off on Natural History of Microperimetry and Optical Coherence Tomography in USH2A-Retinopathy: A Structure-Function Association Study

PURPOSE To describe the natural history of optical coherence tomography (OCT) and mesopic microperimetry (MP) parameters in the Rate of Progression of USH2A -related Retinal Degeneration (RUSH2A) study. DESIGN Multicenter,…

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Reply to Comment on: Dropped Lens Fragments Retrieval Using Endoscopy-Assisted Pars Plana Vitrectomy in Patients With Corneal Opacity

Jul 26, 2025 by in CARDIOLOGY Comments Off on Reply to Comment on: Dropped Lens Fragments Retrieval Using Endoscopy-Assisted Pars Plana Vitrectomy in Patients With Corneal Opacity

We thank Dr Fikret Ucar for his interest on our study “Dropped Lens Fragments Retrieval Using Endoscopy-Assisted Pars Plana Vitrectomy in Patients With Corneal Opacity.” We appreciate the opportunity of…

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