Advances and Major Points of Emphasis 1. Definition of the spectrum of progressive clinical manifestations attributable to renovascular disease 2. Recognition that moderate reductions in renal blood flow do not…
Hypertension resulting from mineralocorticoid excess can be categorized based on levels of renin and aldosterone ( Box 14.1 ). Aldosterone, deoxycorticosterone, and cortisol are the three major mineralocorticoid receptor ligands….
Because patients whose blood pressure (BP) rises to unhealthy levels usually have no symptoms to suggest the presence of this condition the only way to detect the “silent killer” is…
Endocrine disorders account for about 5% to 10% of secondary hypertension. Pheochromocytoma and paraganglioma tumors are a well-established, albeit rare, cause of secondary hypertension. Pheochromocytomas and paragangliomas are tumors of…
Before the early 1970s, intraarterial recordings provided the only means of following changes in blood pressure (BP) during the typical activities of daily living over a period of time. The…
Approximately one-third of the Western population has hypertension, and this disease becomes more frequent with aging. This disease is also a major risk factor for cardiovascular disease, causing stroke, heart…
Despite the fact that conventional measurement of blood pressure (BP) in the office (OBP) has been the cornerstone for hypertension diagnosis and management for decades, it is recognized that this…
Hypertension is a polygenetic disorder provoked by remediable (e.g., sodium intake) as well as unmodifiable factors (e.g., aging). It accounts for up to half of cardiovascular events and is the…
Acknowledgments The authors’ research was supported by grants from the National Heart, Lung and Blood Institute (PO1 HL51971), National Institute of General Medical Sciences (P20 GM104357), National Institute of Diabetes…
Hypertension genetics is of interest to different health care professionals: The clinician is often embarrassed by patient questioning on the origins of the blood pressure (BP) elevation in the absence…
