Design and rationale of aspirin versus aspirin and fondaparinux prior to early invasive strategy in patients with NSTEMI: The FOXY trial

Jun 27, 2026 by in CARDIOLOGY Comments Off on Design and rationale of aspirin versus aspirin and fondaparinux prior to early invasive strategy in patients with NSTEMI: The FOXY trial
ABSTRACT Background Current guidelines recommend a combination therapy with aspirin and a parenteral anticoagulant in patients with non-ST-elevation myocardial infarction (NSTEMI) prior to invasive assessment. However, these recommendations are based…
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Developing therapeutics for rare cardiovascular diseases

Jun 27, 2026 by in CARDIOLOGY Comments Off on Developing therapeutics for rare cardiovascular diseases
ABSTRACT Rare cardiovascular diseases, while individually uncommon, collectively affect millions of people worldwide and are associated with significant morbidity, mortality, and economic burden. Despite this considerable impact, most rare cardiovascular…
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Catheter-based left atrial appendage CLOSURE in patients with atrial fibrillation at high risk of stroke and bleeding as compared to best medical therapy: Rationale and design of the prospective randomized CLOSURE-AF trial

Jun 27, 2026 by in CARDIOLOGY Comments Off on Catheter-based left atrial appendage CLOSURE in patients with atrial fibrillation at high risk of stroke and bleeding as compared to best medical therapy: Rationale and design of the prospective randomized CLOSURE-AF trial
ABSTRACT Background Percutaneous catheter‐based left atrial appendage (LAA) closure is a potential alternative to oral anticoagulation for stroke prevention in patients with atrial fibrillation (AF). The effectiveness and safety of…
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Beta-blocker side-effects in clinical practice: A nationwide approach

Jun 27, 2026 by in CARDIOLOGY Comments Off on Beta-blocker side-effects in clinical practice: A nationwide approach
Highlights • In a nationwide cohort of patients treated with beta-blockers for hypertension, we uncovered clinically relevant increased risks of depression, anxiety/insomnia, gastrointestinal side-effects, and dizziness/fainting compared with calcium-channel blockers….
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Artificial intelligence-enabled electrocardiogram guidance for pulmonary valve replacement timing in repaired tetralogy of Fallot

Jun 27, 2026 by in CARDIOLOGY Comments Off on Artificial intelligence-enabled electrocardiogram guidance for pulmonary valve replacement timing in repaired tetralogy of Fallot
Highlights • Pre-PVR AI-ECG was predictive of post-PVR survival in patients with rTOF. • AI-ECG complements imaging biomarkers for PVR risk stratification. • AI-ECG may help physicians to safely defer…
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Association between conversion from an initial shockable rhythm to pulseless electrical activity before extracorporeal cardiopulmonary resuscitation and outcome: A secondary analysis of the SAVE-J II study

Jun 27, 2026 by in CARDIOLOGY Comments Off on Association between conversion from an initial shockable rhythm to pulseless electrical activity before extracorporeal cardiopulmonary resuscitation and outcome: A secondary analysis of the SAVE-J II study
Highlights • The rate of patients with favorable neurological outcomes was lower in patients who converted to PEA than in those with a sustained shockable rhythm (12.9 % vs 26.4…
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Relationship between left atrial stiffness, pulmonary congestion, and impaired aerobic capacity in adults with repaired coarctation of aorta

Jun 27, 2026 by in CARDIOLOGY Comments Off on Relationship between left atrial stiffness, pulmonary congestion, and impaired aerobic capacity in adults with repaired coarctation of aorta
ABSTRACT Background Left atrial (LA) stiffness is linked to pulmonary congestion and exercise intolerance in patients with acquired form of heart failure but has not been studied in adults with…
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