Cell Cycle and Vascular Targets for Radiotherapy
Cell Cycle and Vascular Targets for Radiotherapy Luigi Moretti Sebahat Ocak Dennis E. Hallahan Bo Lu CELL CYCLE TARGETS FOR RADIOTHERAPY The cell cycle checkpoints ensure that cells replicate their…
Mouse Models of Lung Cancer
Mouse Models of Lung Cancer Ambra Pozzi Lung cancer has increased in incidence throughout the 20th century and is now the most common cancer in the Western World. Compared to…
Lung Cancer and Its Microenvironment
Lung Cancer and Its Microenvironment Marie Wislez Jacques Cadranel Jonathan M. Kurie The association between inflammation and cancer was identified in the 19th century. Initially, it was believed that leukocyte…
Examining the Cancer Stem Cell Hypothesis in Human Lung Cancers
Examining the Cancer Stem Cell Hypothesis in Human Lung Cancers Kerstin W. Sinkevicius Stephen J. Curtis Carla F. Kim The cancer stem cell (CSC) hypothesis, which suggests that tumors are…
Applications of Proteomics to the Management of Lung Cancer
Applications of Proteomics to the Management of Lung Cancer Pierre P. Massion David P. Carbone Lung cancer is the third most common cancer in the United States, yet it causes…
Molecular Prognostication of Lung Cancer
Molecular Prognostication of Lung Cancer Betty C. Tong David H. Harpole Jr At present, the best prognostic indicator of long-term survival for patients with lung cancer is tumor stage. The…
Molecular Events Surrounding the Angiogenic Switch of Lung Cancer
Molecular Events Surrounding the Angiogenic Switch of Lung Cancer Jair Bar Amir Onn Roy S. Herbst Multicellular organisms such as humans require a complex vascular system to supply cells with…
Epigenetic Changes in Lung Cancer: Pathobiological and Clinical Aspects
Epigenetic Changes in Lung Cancer: Pathobiological and Clinical Aspects Ite A. Laird-Offringa Within a decade after the publication of the first human genome sequence,1 and even before a full understanding…
Genomic Alterations in Lung Cancer
Genomic Alterations in Lung Cancer Marileila Varella Garcia Lung cancer has been the leading cause of cancer-related morbidity and mortality worldwide.1 These tumors are classified into two major clinicopathological categories,…
An Overview of the Molecular Biology of Lung Cancer
An Overview of the Molecular Biology of Lung Cancer Jill E. Larsen Monica Spinola Adi F. Gazdar John D. Minna Lung cancer cells have defects in the regulatory circuits that…
