Lymphangioleiomyomatosis Timothy C. Allen MD, JD Lymphangioleiomyomatosis is a rare disease characteristically found in women of childbearing age, presenting with shortness of breath, cough, recurrent pneumothoraces, and chylothorax. Patients demonstrate…
Idiopathic Interstitial Pneumonias Timothy C. Allen MD, JD Philip T. Cagle MD The idiopathic interstitial pneumonias include usual interstitial pneumonia (UIP, the pathologic correlate of idiopathic pulmonary fibrosis, or IPF),…
Pneumoconioses Timothy C. Allen MD, JD Philip T. Cagle MD The pneumoconioses are a group of diseases characterized by lung parenchymal changes due to inhalation of inorganic dusts. The exposures…
Inflammatory Bowel Disease Anna Sienko MD Pulmonary manifestations in inflammatory bowel disease, both in Crohn disease and ulcerative colitis, are well documented. Best characterized and seen more often in Crohn…
Drug Reactions Timothy C. Allen MD, JD Jaishree Jagirdar MD Philip T. Cagle MD Pulmonary reactions to drugs may be idiosyncratic or dose related and include diffuse alveolar damage, intra-alveolar…
Collagen Vascular Diseases Timothy C. Allen MD, JD Jaishree Jagirdar MD Philip T. Cagle MD Collagen vascular diseases that may involve the lungs include rheumatoid arthritis, systemic lupus erythematosus, progressive…
Hypersensitivity Pneumonitis Armando E. Fraire MD Philip T. Cagle MD Broadly defined as a state of exaggerated immune response to a wide variety of antigenic substances, hypersensitivity pneumonitis refers to…
Sarcoidosis Armando E. Fraire MD Sarcoidosis, a systemic disease of unknown etiology often affecting the lungs and mediastinal lymph nodes, is characterized histopathologically by granulomas that are found distinctively along…
Pulmonary Alveolar Proteinosis Anna Sienko MD Philip T. Cagle MD Pulmonary alveolar proteinosis, also termed alveolar lipoproteinosis, represents an autoimmune defect of the alveolar macrophages to remove surfactant with the…
Lipid Pneumonia Timothy C. Allen MD, JD Roberto Barrios MD Lipid pneumonia, also termed endogenous lipoid pneumonia, postobstructive pneumonia, or “golden pneumonia,” occurs due to the escape of normally occurring…
