Several epidemiologic studies have demonstrated that plasma low-density lipoprotein cholesterol (LDL-C) profile is a key risk indicator for coronary heart disease (CHD). However, almost half of all patients with CHD…
Despite recent therapeutic advances, significant residual risk for in-hospital mortality persists among patients admitted with acute myocardial infarction (MI). Low levels of high-density lipoprotein cholesterol (HDL-C), a known independent predictor…
Trauma-related failure of a continuous-flow left ventricular assist device (LVAD) has not previously been reported. We present 4 cases in which LVAD complications were likely caused by external trauma and…
Lazar Greenfield was born in Houston, Texas, in 1934, and that is where he grew up. He attended public schools and then Rice University before graduating with honors from Baylor…
Treatment strategies for symptomatic patients with obstructive hypertrophic cardiomyopathy (HC) represent an important component of the overall management armamentarium for this complex genetic disease, and have generated considerable debate in…
Evidence-based medicine demands considerable time and decision-making skills to navigate through the proliferating data. A hierarchical “pyramid of evidence” has been formulated to help categorize data quality. The hierarchical data…
Data concerning the prevalence, risk factors, and prognostic significance of hemoptysis in pediatric pulmonary arterial hypertension (PAH) are scarce. A Dutch national cohort of 74 children with either idiopathic or…
It is still very much a clinical enigma of when to recommend aortic valve replacement for many patients with aortic stenosis. Most clinical decisions have been based on the Ross…
Pulmonary oxygen uptake (˙VO2p) ( V ˙ O 2 p ) at exercise onset is severely delayed in heart transplant recipients (HTRs). The role of exercise training to improve ˙VO2p…
Through bound apolipoprotein A-I (apoA-I), high-density lipoprotein cholesterol (HDL-C) activates endothelial nitric oxide synthase, inducing vasodilation. Because patients with sickle cell disease (SCD) have low apoA-I and endothelial dysfunction, we…
