Atrioventricular Conduction Abnormalities: Delays, Blocks, and Dissociation Syndromes

Chapter 17 Atrioventricular Conduction Abnormalities Delays, Blocks, and Dissociation Syndromes


With normal cardiac anatomy (see Chapter 1), the only means of electrical communication between the atria and ventricles is via the specialized conduction system of the heart. This relay network comprises the atrioventricular (AV) node, which is connected to the His bundle, which in turn is connected to the bundle branches (Fig. 17-1). The atria and ventricles are otherwise electrically isolated from each other by connective tissue in the indented rings (grooves) between the upper and lower chambers. The key exception occurs with Wolff-Parkinson-White (WPW) preexcitation syndrome, described in Chapters 12 and 14.



The slight physiologic delay, reflected in the normal PR interval, between atrial and ventricular activation allows the ventricles optimal time to fill with blood during and after atrial contraction. Excessive slowing or actual interruption of electrical signal propagation across the heart’s conduction system is abnormal and termed AV (atrioventricular) block or heart block. The closely related (and often confusing to students and experienced clinicians!) topic of AV dissociation is discussed at the end of this chapter and in Chapter 10.




What is the Degree of AV Block?


Depending on the severity of conduction impairment, there are three major degrees of AV block:



Two other important subtypes of second-degree AV block, namely 2:1 block and high-grade block (also referred to as “advanced second-degree AV block”) will also be discussed.



Prolonged PR Interval (First-Degree AV Block)


First-degree AV block (Fig. 17-2) is characterized by a P wave (usually sinus in origin) followed by a QRS complex with a uniformly prolonged PR interval greater than 200 msec. The preferred term is PR interval prolongation because the signal is not really blocked, but rather it is delayed. The PR interval can be slightly prolonged (e.g., 240 msec) or it can become markedly long (up to 400 msec or longer).




Second-Degree AV Block Syndromes


Second-degree AV block is characterized by intermittently “dropped” QRS complexes. There are two major subtypes of second-degree AV block: Mobitz type I (AV Wenckebach) and Mobitz type II.


With Mobitz type I, the classic AV Wenckebach pattern (Figs. 17-3 and 17-4), each stimulus from the atria has progressive difficulty traversing the AV node to the ventricles (i.e., the node becomes increasingly refractory). Finally, the atrial stimulus is not conducted at all, such that the expected QRS complex is blocked (“dropped QRS”). This cycle is followed by relative recovery of the AV junction, and then the whole cycle starts again.




The characteristic ECG signature of AV Wenckebach block, therefore, is progressive lengthening of the PR interval from beat to beat until a QRS complex is dropped. The PR interval following the nonconducted P wave (the first PR interval of the new cycle) is always shorter than the PR interval of the beat just before the nonconducted P wave.


The number of P waves occurring before a QRS complex is “dropped” may vary. The nomenclature is in terms of a ratio that gives the number of P waves to QRS complexes in a given cycle. The numerator is always one higher than the denominator. In many cases just two or three conducted P waves are seen before one is not conducted (e.g., 3:2, 4:3 block). In other cases, longer cycles are seen (e.g., 5:4, 10:9, etc.).


As you can see from the examples, the Wenckebach cycle also produces a distinct clustering of QRS complexes separated by a pause (the dropped beat). Any time you encounter an ECG with this type of group beating, you should suspect AV Wenckebach block and look for the diagnostic pattern of lengthening PR intervals and the presence of a nonconducted P wave. As discussed in the following text, infranodal second-degree AV block (Mobitz type II) also demonstrates grouped beating with dropped QRS complexes, but without significant progressive PR interval prolongation (Fig. 17-5).



Caution! Be careful not to mistake group beating due to blocked atrial premature beats (APBs) for second-degree AV block. In the former, the nonconducted P waves come “early”; in the latter they come “on time” (see Chapter 14).


Mobitz type II AV block is a rarer and more serious form of second-degree heart block. Its characteristic feature is the sudden appearance of a single, nonconducted sinus P wave without (1) the progressive prolongation of PR intervals seen in classic Mobitz type I AV block, and (2) without the noticeable (≤40 msec) shortening of the PR interval in the beat following the nonconducted P wave versus the PR before, as seen with type I block.


A subset of second-degree heart block occurs when there are multiple consecutive nonconducted P waves present (e.g., P-QRS ratios of 3:1, 4:1, etc.). This finding is referred to as high-degree (or advanced) AV block. It can occur at any level of the conduction system (Fig. 17-6). A common mistake is to call this pattern Mobitz II block.




Third-Degree (Complete) AV Block


First- and second-degree heart blocks are examples of incomplete block because the AV junction conducts some stimuli to the ventricles. With third-degree, or complete, heart block, no stimuli are transmitted from the atria to the ventricles. Instead, the atria and ventricles are paced independently. The atria often continue to be paced by the sinoatrial (SA) node. The ventricles, however, are paced by a nodal or infranodal escape pacemaker located somewhere below the point of block. The resting ventricular rate with complete heart block may be around 30 beats/min or lower or as high as 50 to 60 beats/min. This situation, when there is no “cross-talk” between the atria and ventricles and each of them is driven independently by a separate pacemaker at a different rate, is one example of AV dissociation. In the setting of complete heart block, AV dissociation almost always produces more P waves than QRS complexes (Box 17-1). However, as discussed later, AV dissociation is not unique to complete heart block.



Examples of complete heart block are shown in Figures 17-7 and 17-8.


Jun 11, 2016 | Posted by in CARDIOLOGY | Comments Off on Atrioventricular Conduction Abnormalities: Delays, Blocks, and Dissociation Syndromes

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