Pathogenesis of COPD 3: Oxidative Stress – Is There a Possibility of Developing New Drugs from the Standpoint of This Pathogenetic Mechanism?

Sep 25, 2017 by in RESPIRATORY Comments Off on Pathogenesis of COPD 3: Oxidative Stress – Is There a Possibility of Developing New Drugs from the Standpoint of This Pathogenetic Mechanism?

Exogenous source Origin Cigarette smoking Cigarette smoke Air pollution (ozone, SO2, NO2) Polluted air Infection Bacteria/virus/fungus/protozoa Endogenous source Location Electron transport chain of mitochondria Endothelial cells Xanthine oxidase system Airway…

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Nutritional Therapy for COPD: What Is the Present State of Nutritional Therapy and Is There a Possibility of Developing New Drugs?

Sep 25, 2017 by in RESPIRATORY Comments Off on Nutritional Therapy for COPD: What Is the Present State of Nutritional Therapy and Is There a Possibility of Developing New Drugs?

Adequate calories to exceed basal energy expenditure slightly Small, frequent meal Timing the main meal to corresponed to the time requiring high energy More protein and fat and less carbohydrate…

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Transposition of the Great Arteries

Sep 20, 2017 by in CARDIOLOGY Comments Off on Transposition of the Great Arteries

Fig. 20.1 Transposition of the great arteries Two main hypotheses are recognized (Marino et al. 2002). Gore and Edwards proposed that TGA was caused by the lack of the normal…

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Coagulation Monitoring

Sep 20, 2017 by in CARDIOLOGY Comments Off on Coagulation Monitoring

Compensates the reduction of oxygen-carrying capacity by the anemia by increasing cardiac output (limited response) Adaptation to the low intrauterine oxygen tension by increasing hematocrit through Hb F (70 %…

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Cardiac Anesthesia in Infants and Children: Postoperative Bleeding and Coagulation Management

Sep 20, 2017 by in CARDIOLOGY Comments Off on Cardiac Anesthesia in Infants and Children: Postoperative Bleeding and Coagulation Management

Preoperative factors Age Neonates Prematures Low birth weight Undeveloped coagulation system and calcium hemostasis Comorbidities Acquired coagulopathies Dilution and trauma post CPB Renal or hepatic insufficiency Congenital coagulopathies von Willebrand…

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Coronary Artery Anomalies

Sep 20, 2017 by in CARDIOLOGY Comments Off on Coronary Artery Anomalies

Fig. 31.1 Illustration of normal coronary anatomy showing the LMT arising from the left coronary sinus and the RCA off the right coronary sinus. The LMT after a short segment…

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