Figure 14-1. Photo of a child having infant lung function testing. The child has been sedated with chloral hydrate and has had a mask with pneumotachograph attached to their face…
Figure 12-1. Simplified schematic view of the ventral mammalian brain stem. Rhythm generation resides mainly in the pre-Bötzinger (pre-BötC) complex, while pattern formation resides more caudally in the ventral respiratory…
Figure 9-1. (A) Changes in FRC of rabbit pups (30 days) treated with either an epithelial sodium channel blocker (amiloride; filled circles) or saline (open circles) and mechanically ventilated from…
Figure 6-1. Tracheal agenesis with bronchoesophageal fistula. An infant boy was born at 36 weeks gestation after a pregnancy complicated by idiopathic polyhydramnios, a prenatal evaluation showing normal chromosome karyotype,…
Figure 17-1. An illustration of the concept of the lung structure maintenance program. There are several homeostatic balances that contribute to lung cell growth and repair in response to environmental…
Figure 7-1. Airway branching with gestational age. The stages of lung development and the development of the bronchial tree. On average an airway of a human lung ends after approximately…
Figure 5-1. Expression of nAChR in fetal monkey airway (134 days gestation). (A) α4 nAChR immunostaining (purple) in airway epithelial cells and submucosal glands (200x); (B) β2 immunostaining (purple) in…
Figure 8-1. Composition of surfactant from bronchoalveolar lavage. Representative values for surfactant from adult mammalian species. The primary surface active components are the saturated phosphatidylcholine and the hydrophobic proteins SP-B…
Figure 10-1. Causes of poor lung growth. Lung growth is complex and modulated by multiple processes. Poor lung growth may result from maternal, fetal, placental, environmental, and/or genetic factors. Reprinted…
Figure 15-1. The perinatal environment influences saccular and alveolar lung development. Mammalian lung development proceeds through five stages that culminate in the formation of a dichotomously branched organ with many…
