Epigenetic Changes in Lung Cancer: Pathobiological and Clinical Aspects Ite A. Laird-Offringa Within a decade after the publication of the first human genome sequence,1 and even before a full understanding…
Genomic Alterations in Lung Cancer Marileila Varella Garcia Lung cancer has been the leading cause of cancer-related morbidity and mortality worldwide.1 These tumors are classified into two major clinicopathological categories,…
An Overview of the Molecular Biology of Lung Cancer Jill E. Larsen Monica Spinola Adi F. Gazdar John D. Minna Lung cancer cells have defects in the regulatory circuits that…
Genetic Susceptibility to Lung Cancer Christopher I. Amos Joan E. Bailey-Wilson Lung cancer is the most common cause of cancer death in the United States1 with 162,000 deaths estimated for…
Nontobacco-Related Lung Carcinogenesis Tze-Ming Benson Chen Ware G. Kuschner Lung cancer is estimated to cause 17,000 to 26,000 deaths among nonsmokers annually in the United States.1 Secondhand smoke exposure explains…
The Tobacco Epidemic Carolyn Dresler Tobacco has a fascinating history. Tobacco is native only to the Americas and its scientific names include Nicotiana rustica and Nicotiana tabacum.1 Tobacco was first…
The Etiology and Epidemiology of Lung Cancer David Schottenfeld Lung cancer is the leading cause of cancer mortality in men and women in the United States, accounting for an estimated…
