Bronchiectasis
Bronchiectasis Allen P. Burke, M.D. Definition Bronchiectasis is a descriptive term for irreversibly dilated, thickened, and inflamed bronchi. Diffuse bronchiectasis is a hallmark of cystic fibrosis. Non-cystic fibrosis bronchiectasis is…
Chronic Bronchitis
Chronic Bronchitis Allen P. Burke, M.D. General Terminology Chronic bronchitis is a descriptive term, when used pathologically, that indicates chronic inflammation of large airways of any cause (Fig. 30.1). In…
Diffuse Alveolar Hemorrhage
Diffuse Alveolar Hemorrhage Allen P. Burke, M.D. Marie-Christine Aubry, M.D. Terminology and General Concepts Diffuse alveolar hemorrhage (DAH) is caused by a group of disorders that result in hemorrhage originating…
Pulmonary Alveolar Proteinosis
Pulmonary Alveolar Proteinosis Allen P. Burke, M.D. Fabio R. Tavora, M.D., Ph.D. Classification and Terminology Rosen, Castleman, and Liebow described pulmonary alveolar proteinosis (PAP) more than 50 years ago.1 Currently,…
Pulmonary Amyloidosis
Pulmonary Amyloidosis Marie-Christine Aubry, M.D. Allen P. Burke, M.D. Definition Amyloidosis is a heterogeneous group of disorders that share one feature in common: deposition of amyloid, a protein in an…
Eosinophilic Pneumonia and Related Conditions
Eosinophilic Pneumonia and Related Conditions Allen P. Burke, M.D. Eosinophilic Lung Disease Terminology Eosinophilic lung disease forms a rare spectrum of idiopathic and secondary conditions that may be acute or…
Aspiration Pneumonia
Aspiration Pneumonia Allen P. Burke, M.D. Fabio R. Tavora, M.D., Ph.D. Marie-Christine Aubry, M.D. Aspiration and Aspiration Pneumonia Clinical and Radiologic Findings Recurrent aspiration of gastric contents, or chronic occult…
Pulmonary Langerhans Cell Histiocytosis
Pulmonary Langerhans Cell Histiocytosis Marie-Christine Aubry, M.D. Anja C. Roden, M.D. Allen P. Burke, M.D. Terminology Pulmonary Langerhans cell histiocytosis (PLCH) is an interstitial lung disease characterized by an abnormal…
Hypersensitivity Pneumonia
Hypersensitivity Pneumonia Marie-Christine Aubry, M.D. Allen P. Burke, M.D. Seth Kligerman, M.D. Hypersensitivity Pneumonia Terminology and Definition Hypersensitivity pneumonia, also known as hypersensitivity pneumonia1,2 and extrinsic allergic alveolitis,3 is an…