Abstract Persistent pulmonary hypertension of the newborn (PPHN) is a syndrome of failed circulatory adaptation at birth due to the delay in or impairment of the normal fall in pulmonary…
Abstract Light-based approaches to the assessment of a tissue’s oxygen status are attractive to the clinician because they provide the possibility of continuous noninvasive measurements. For example, pulse oximetry, which…
Abstract In the absence of outcome-based evidence to guide circulatory support in the newborn, a logical approach is one that uses individual- or precision-based therapy. That is, one should try…
Abstract There is a progressive adoption of point of care ultrasound (POCU) performed by acute care physicians in many clinical areas including the neonatal intensive care unit. There has been…
Abstract This chapter describes a number of methods for measurement of blood flow, nearly all tried in newborns because they had worked in adults. Most often they have been applied…
Abstract The goal of predictive monitoring is to predict or detect adverse events far enough in advance of conventional detection methods to allow for earlier treatment and improved outcomes. The…
Abstract Persistent pulmonary hypertension is the term used to describe a spectrum of pathophysiological changes that result in hypoxic respiratory failure. A number of underlying physiologies contribute to this overarching…
Abstract Peri/intraventricular hemorrhage (P/IVH), a major complication of prematurity, increases the risk of mortality and is associated with significant short and long-term morbidities. Pathogenesis of P/IVH is complex and multifactorial….
Abstract This chapter describes some of the multiple molecular mechanisms that regulate the contraction of the vascular smooth muscle cell and thus the arterial vascular tone. This tone is central…
Abstract While umbilical cord clamping (UCC) at birth is considered to be an innocuous act, whether or not it is depends upon when it occurs during the infant’s transition to…
