Fig. 3.1 Molecular formula of Ezetimibe (C24H21F2NO3) Fig. 3.2 Mechanism of Ezetimibe. Both dietary cholesterol consumption and intestinal cholesterol absorption contribute to plasma cholesterol concentrations. Ezetimibe lowers cholesterol absorption and…
Fig. 13.1 Prevalence, treatment and control of combined hypertension and hypercholesterolemia in UC adults by age group (a) and sex (b). Hypertension and hypercholesterolemia: prevalence (dotted bars), treatment (slashed bars),…
Fig. 5.1 Chemical structure of ALA, EPA, and DHA as free fatty acids. Note that all bonds present are all cis isomers ALA is found in both animal and plants…
Fig. 1.1 Pathway for bile acid biosynthesis. In humans bile acids are conjugated to glycine, while in rodents they are conjugated to taurine (Reproduced with permission from Russell [50]) The…
Fig. 9.1 Role of PCSK9 in the regulation of LDL-C concentrations. (a) PCSK9 binds to LDL Receptor (LDLR) and, upon internalization of the LDL/LDLR complex, directs LDLR to lysosomal degradation,…
Fig. 8.1 Types of familial hypercholesterolemias FH includes heterozygous FH (HeFH), the less severe form, with a prevalence of ~1:200–1:500, and homozygous FH (HoFH), a much rarer condition, with a…
© Springer International Publishing Switzerland 2015Maciej Banach (ed.)Combination Therapy In Dyslipidemia10.1007/978-3-319-20433-8_17 17. Conclusions and Take Home Message Maciej Banach1 (1) Department of Hypertension, WAM University Hospital in Lodz, Medical University of Lodz, Zeromskiego 113, Lodz,…
© Springer International Publishing Switzerland 2015Maciej Banach (ed.)Combination Therapy In Dyslipidemia10.1007/978-3-319-20433-8_16 16. Drug Evaluation: Olmesartan Medoxomil + Rosuvastatin for the Treatment of Dyslipidemia and Concomitant Risk Factors: A Chance for Better Compliance? Joanna Gozdzikiewicz-Lapinska1 and…
Fig. 15.1 The benefits of fenofibrate/simvastatin combination therapy in different clinical dyslipidemic patterns Although some evidence suggests a possible heightened risk for myopathy and rhabdomyolysis [11], the combination of statin…
© Springer International Publishing Switzerland 2015Maciej Banach (ed.)Combination Therapy In Dyslipidemia10.1007/978-3-319-20433-8_14 14. The Cardiovascular Polypill in the Prevention of Cardiovascular Disease Melvin Lafeber1 (1) Department of Vascular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands…
