Clinical Assessment of Sequential Slow and Ultra-Slow Thrombolysis Approaches for Stuck Prosthetic Valve Thrombosis as a Novel Dose-Adjusted Regimen Analysis (The Multicenter CASSANDRA Study)

Aug 8, 2026 by in CARDIOLOGY Comments Off on Clinical Assessment of Sequential Slow and Ultra-Slow Thrombolysis Approaches for Stuck Prosthetic Valve Thrombosis as a Novel Dose-Adjusted Regimen Analysis (The Multicenter CASSANDRA Study)
Thrombolytic therapy (TT) using low-dose, slow, and ultra-slow infusions of tissue-type plasminogen activator (tPA) has become an established first-line treatment for prosthetic valve thrombosis (PVT). However, PVT with stuck valves…
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Safety and Effectiveness of the Santreva™-ATK Endovascular Revascularization Catheter in the RESTOR-1 Peripheral CTO Crossing Pivotal Study

Aug 8, 2026 by in CARDIOLOGY Comments Off on Safety and Effectiveness of the Santreva™-ATK Endovascular Revascularization Catheter in the RESTOR-1 Peripheral CTO Crossing Pivotal Study
Data on recanalization of femoropopliteal (FP) chronic total occlusions (CTOs) and characterization of the traversed crossing track are limited. The AngioSafe Peripheral-2 CTO Crossing Catheter (Santreva™-ATK) was evaluated in a…
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Anomalous Attachment of the Posterior Mitral Annulus to the Crest of the Left Ventricle in Patients With Mitral Annular Disjunction (MAD) and Mitral Valve Prolapse

Aug 8, 2026 by in CARDIOLOGY Comments Off on Anomalous Attachment of the Posterior Mitral Annulus to the Crest of the Left Ventricle in Patients With Mitral Annular Disjunction (MAD) and Mitral Valve Prolapse
The purpose of this study is to determine the site of attachment of the posterior mitral annulus to the left ventricle in patients with mitral annular disjunction (MAD) and mitral…
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Imaging to Rule Out Thrombus Before Ablation

Aug 8, 2026 by in CARDIOLOGY Comments Off on Imaging to Rule Out Thrombus Before Ablation
We congratulate Hu et al for reporting an important multicenter randomized trial evaluating intracardiac echocardiography versus transesophageal echocardiography for thrombus screening before atrial fibrillation ablation. Multiple key points merit further…
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Patient-Reported Outcomes Using Win Ratio Analysis: A Post Hoc Analysis from the Randomized ENVISAGE-TAVI AF Trial

Aug 8, 2026 by in CARDIOLOGY Comments Off on Patient-Reported Outcomes Using Win Ratio Analysis: A Post Hoc Analysis from the Randomized ENVISAGE-TAVI AF Trial
Highlights • Effects of edoxaban versus VKAs on PROs were assessed using a WR approach • PACT-Q2 captured patient-perceived convenience/satisfaction with anticoagulants • WR adds interpretation of meaningfulness and drivers…
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