Fig. 12.1 (a) hMPV infection. Note severe bronchiolitis with ulcerated bronchiolar epithelium. (b) Higher power showing accumulation of intra-alveolar macrophages. (c) Note pulmonary congestion and mild interstitial lymphocytic inflammation. (d)…
Fig. 11.1 Panel A: Respiratory syncytial virus pneumonia. Note cuff-like intense bronchiolar and peribronchiolar inflammatory reaction. Hematoxylin and eosin. Panel B: Same bronchiole illustrated in Panel A showing RSV antigen….
Fig. 7.1 Varicella virus. Round to hexagonal or “stop sign”-shaped, targetoid viral particles, cell culture media. Original magnification × 57000 (Courtesy of Dr. Richard Kradin and Dr. William Taylor, with…
Fig. 2.1 Antiviral action of interferon: Interferon (IFN) synthesis and release are often induced by a virus infection when cellular sensors recognize their pathogen-associated molecular patterns such as double-stranded RNA…
Figure 1.1 Factors involved in the pathophysiology of pulmonary arterial hypertension Vasoconstriction In accordance with Poiseuille’s law the flow of blood through a vessel is proportional to its radius to…
Figure 3.1 Survival plot before and after the advent of targeted vasodilator therapy, using REVEAL registry data (2012) of idiopathic and familial PAH matched to that from National Institutes of…
Figure 2.1 Histology showing remodelled pulmonary arteries in idiopathic pulmonary arterial hypertension (iPAH). Photographs of paraffin-embedded haematoxylin and eosin-stained human lung sections from patients with iPAH following lung transplantation. Medium…
Figure 4.1 Material removed at pulmonary thromboendarterectomy, courtesy of Dr J Haney, Duke University Medical Center Reperfusion is followed by a second period of circulatory arrest to allow completion of…
8. Madden B, Hodson M, Tsang V, Radley-Smith R, Khagani A, Yacoub M. Intermediate term results of heart-lung transplantation for cystic fibrosis. Lancet. 1992;339:1583–7.PubMedCrossRef
