Abstract Exercise in children is not merely play; rather, it is a critical environmental and physiological perturbation that has a profound effect on growth and development in health and disease….
Abstract This chapter discusses the transgenerational, antenatal, and early childhood factors that affect lung development across the life course. The consequences of these adverse influences may be direct, or secondary…
Abstract Lung function testing in early life can provide information on lung growth and development and can help clinicians in the decision making process. However, the techniques available in infants…
Abstract Children and adolescents with chronic respiratory disease become adults with chronic respiratory disease. As a result of ongoing improvements in health care, this is now increasingly the norm rather…
Abstract Patient-reported outcomes (PROs) are instruments that evaluate daily functioning and health outcomes from the patient’s perspective. If developed using standardized procedures (FDA Guidance, 2009), they can be used as…
Abstract Pediatric pulmonologists are frequently consulted on the child with “too many” respiratory infections. Considering the volume of air, particulates, chemicals, and potential airborne pathogens inspired with each breath, the…
Abstract The nature and development airway inflammation may be driven by numerous factors, including pathogenic infections, pollution, or even relatively innocuous inhaled particles, such as allergens. A robust inflammatory response…
Abstract Bronchoscopy is a powerful (and often underutilized) tool for the diagnosis and management of airway and pulmonary problems in infants and children. Both rigid and flexible instruments are available…
Abstract Disorders of the Respiratory Tract in Children outlines the congenital abnormalities and diseases that affect the respiratory health of children. A thorough understanding of the structure, function, and development…
Abstract Pulmonary surfactant is a complex substance with multiple functions in the microenvironments of the alveoli and small airways. The traditional functions of surfactant are biophysical activities to keep the…
