Abstract Children with diffuse and interstitial lung disease (chILD) comprise a group of rare disorders with significant morbidity and mortality. Individually these disorders are rare but collectively they create a…
Abstract Upper airway disease, including chronic rhinitis and rhinosinusitis, affect most children with asthma. Over the past two decades, our understanding of the connection between the nose, paranasal sinuses, and…
Abstract Focus on drug development for asthma has been on development of immunomodulator therapies, with the hopes that they can eventually alter the natural course of asthma. This review focuses…
Abstract Most pediatric asthma is easily treated with low-dose inhaled corticosteroids, occasionally combined with a long-acting bronchodilator, provided the medications are administered regularly and correctly. If the child does not…
Abstract Improvements in the intensive care and monitoring of patients with serious illnesses led to a greater appreciation of the significance of fluid movement into the lung as a complication…
Abstract Wheeze in preschool children (5 years of age and younger) is common. The majority of severe episodes are triggered by viral colds. Unlike atopic asthma in adults and young…
Abstract Bronchiectasis, chronic suppurative lung disease, and protracted bacterial bronchitis (PBB) are increasingly recognized conditions. Bronchiectasis is now again increasingly diagnosed, and its renewed interest has resulted in further in-depth…
Abstract A significant number of children admitted to pediatric intensive care units across the United States receive invasive mechanical ventilation. While respiratory disease in children is a major indication for…
Abstract Lung injury from hydrocarbon aspiration continues to account for a significant proportion of accidental poisonings in children. Severe pneumonitis can occur. Treatment remains largely supportive, and some suggest that…
