CARDIOLOGY

Global Burden of Eye Injuries in Children and Adolescents, 1990 to 2021: A Systematic Analysis From the Global Burden of Disease Study

Jul 26, 2025 by in CARDIOLOGY Comments Off on Global Burden of Eye Injuries in Children and Adolescents, 1990 to 2021: A Systematic Analysis From the Global Burden of Disease Study

Highlights • The incidence of eye injuries in children and adolescents decreased from 1990 to 2021. • Regions with high Socio-Demographic Index exhibited the highest incidence of eye injuries. •…

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Pegcetacoplan Treatment for Geographic Atrophy in Age-Related Macular Degeneration Over 36 Months: Data From OAKS, DERBY, and GALE

Jul 26, 2025 by in CARDIOLOGY Comments Off on Pegcetacoplan Treatment for Geographic Atrophy in Age-Related Macular Degeneration Over 36 Months: Data From OAKS, DERBY, and GALE

HIGHLIGHTS • Pegcetacoplan demonstrated increasing efficacy over time through 36 months. • Pegcetacoplan is the first GA treatment to show benefit in prespecified functional analyses. • Safety outcomes in the…

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Efficacy and Safety of Polypropylene Scleral Suture Fixation of Intraocular Lens in Pediatric Nontraumatic Ectopia Lentis: A Real-World Study

Jul 26, 2025 by in CARDIOLOGY Comments Off on Efficacy and Safety of Polypropylene Scleral Suture Fixation of Intraocular Lens in Pediatric Nontraumatic Ectopia Lentis: A Real-World Study

HIGHLIGHTS • The study focuses on the efficacy and safety of scleral-suture fixation of intraocular lens (SFIOL) in children with nontraumatic ectopia lentis (EL) in a real-world setting. • SFIOL…

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Primary Merkel cell carcinoma of the eyelid

Jul 26, 2025 by in CARDIOLOGY Comments Off on Primary Merkel cell carcinoma of the eyelid

A 70-year-old woman presented to the ophthalmology department with a two-month history of a progressively enlarging mass on her left upper eyelid. She denied visual impairment, ocular redness, or pain….

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Ocular Adverse Events Associated with Pegcetacoplan and Avacincaptad Pegol for Geographic Atrophy: A Population-Based Pharmacovigilance Study

Jul 26, 2025 by in CARDIOLOGY Comments Off on Ocular Adverse Events Associated with Pegcetacoplan and Avacincaptad Pegol for Geographic Atrophy: A Population-Based Pharmacovigilance Study

Highlights • Pegcetacoplan was linked to more adverse events than avacincaptad pegol based on FAERS. • Pegcetacoplan’s safety profile aligns with early clinical trial findings. • Avacincaptad pegol was linked…

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Reply to Comment on: “Epithelial Mapping Efficacy for Subclinical Keratoconus Identification”

Jul 26, 2025 by in CARDIOLOGY Comments Off on Reply to Comment on: “Epithelial Mapping Efficacy for Subclinical Keratoconus Identification”

We appreciate the opportunity to further clarify details from our recent article “Epithelial Mapping Efficacy for Subclinical Keratoconus Identification.” Toprak’s comments regarding our the subclinical keratoconus definition that we used…

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Clinical Characteristics of Patients With Less Common Causes of Leber Congenital Amaurosis/Early-Onset Severe Retinal Dystrophy

Jul 26, 2025 by in CARDIOLOGY Comments Off on Clinical Characteristics of Patients With Less Common Causes of Leber Congenital Amaurosis/Early-Onset Severe Retinal Dystrophy

Purpose To analyze the clinical characteristics, natural history, and genetics of Leber congenital amaurosis (LCA) early-onset severe retinal dystrophy (EOSRD) associated with uncommon genes. Design Single tertiary referral center, retrospective…

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