Effect of preimplant endovascular debulking strategies on the deployment of nitinol self-expanding stents in superficial femoral arteries

Nov 16, 2017 by in CARDIOLOGY Comments Off on Effect of preimplant endovascular debulking strategies on the deployment of nitinol self-expanding stents in superficial femoral arteries

Background The effect of debulking on nitinol self-expanding (n-SES) stent deployment in the superficial femoral artery (SFA) has never been systematically assessed. Objective The objective was to evaluate hemodynamic differences…

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Dethrombosis of lower extremity arteries by local delivery of thrombolysis using the ClearWay transcatheter balloon irrigation system: a feasibility study

Nov 16, 2017 by in CARDIOLOGY Comments Off on Dethrombosis of lower extremity arteries by local delivery of thrombolysis using the ClearWay transcatheter balloon irrigation system: a feasibility study

Background Thrombus is highly prevalent in patients with recent symptoms (<6 months) of claudication or limb ischemia and occluded culprit lower extremity vessels. Treatment of these thrombotic occlusions is challenging….

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Percutaneous lower extremity arterial interventions using plain balloon angioplasty vs. cryoplasty with the PolarCath®: a randomized trial

Nov 16, 2017 by in CARDIOLOGY Comments Off on Percutaneous lower extremity arterial interventions using plain balloon angioplasty vs. cryoplasty with the PolarCath®: a randomized trial

Background Target lesion revascularization (TLR) with primary percutaneous transluminal angioplasty (PTA) vs. cryoplasty (CRYO) in the treatment of de novo infrainguinal disease has not been well defined in randomized trials….

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Very low bleeding rates with local thrombolytic therapy given during percutaneous endovenous intervention for the treatment of deep venous thrombosis

Nov 16, 2017 by in CARDIOLOGY Comments Off on Very low bleeding rates with local thrombolytic therapy given during percutaneous endovenous intervention for the treatment of deep venous thrombosis

Background Patients undergoing administration of thrombolytic therapy for deep venous thrombosis (DVT) have been reported to have major bleeding rates of 5%–10%. These results stem from older data with dosing…

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Percutaneous recanalization of central veins access for pacemaker/cardioverter–defibrillator implantation or upgrade

Nov 16, 2017 by in CARDIOLOGY Comments Off on Percutaneous recanalization of central veins access for pacemaker/cardioverter–defibrillator implantation or upgrade

Background Patients (pts) undergoing pacemaker and/or cardioverter–defibrillator (PM/ICD) implantation/upgrade might have difficult access due to sub/total central vein occlusions, usually related to prior venous manipulation. This study aimed to describe…

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Clinical outcomes following unrestricted use of the everolimus-eluting stent as compared with paclitaxel- and sirolimus-eluting stents

Nov 16, 2017 by in CARDIOLOGY Comments Off on Clinical outcomes following unrestricted use of the everolimus-eluting stent as compared with paclitaxel- and sirolimus-eluting stents

Background There is currently a paucity of data regarding clinical outcomes after everolimus-eluting stent (EES) implantation [compared to paclitaxel-eluting stents (PES) and sirolimus-eluting stents (SES)] in unselected patients with the…

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High on-treatment platelet reactivity is associated with periprocedural myocardial infarction

Nov 16, 2017 by in CARDIOLOGY Comments Off on High on-treatment platelet reactivity is associated with periprocedural myocardial infarction

Background Both high on-treatment platelet reactivity and periprocedural myocardial infarction (MI) are associated with adverse events following percutaneous coronary intervention (PCI). The optimal method of quantifying platelet reactivity remains controversial….

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Treatment of smaller coronary vessels with XIENCE V everolimus-eluting stents in real-world patients: 1-year clinical outcomes from the XIENCE V USA study

Nov 16, 2017 by in CARDIOLOGY Comments Off on Treatment of smaller coronary vessels with XIENCE V everolimus-eluting stents in real-world patients: 1-year clinical outcomes from the XIENCE V USA study

Background Patients with lesions located in small vessels are at increased risk of adverse outcomes after PCI. Improved safety and efficacy have been previously demonstrated with XIENCE V stents in…

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Genetic deficiency of cystathionine gamma-lyase exacerbates myocardial reperfusion injury and is rescued by exogenous hydrogen sulfide

Nov 16, 2017 by in CARDIOLOGY Comments Off on Genetic deficiency of cystathionine gamma-lyase exacerbates myocardial reperfusion injury and is rescued by exogenous hydrogen sulfide

Hydrogen sulfide (H 2 S) is a novel gaseous signaling molecule that up-regulates antioxidants, anti-apoptogens, and promotes cellular survival. In the heart, cystathionine gamma-lyase (CSE) is the primary enzyme for…

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