Background Higher rates of adverse cardiac events have been observed in patients with small vessel disease. In a pooled analysis of the SPIRIT III and IV trials, we compared an…
Background New stent technologies and expanded stent matrices may impact healthcare costs for payers and providers. We evaluated the cost-effectiveness of TAXUS Liberté Long drug-eluting stents (DES) vs. TAXUS Express…
Background Advanced stent platform iterations should be able to demonstrate safety and efficacy advantages over earlier-generation devices while being cost-effective. We developed an economic model to evaluate cost-effectiveness of stent…
Objective Drug-eluting stents (DES) are known to impact vascular functions. The impact of the polymers and the drugs used in DES on the pathways regulating vascular reactivity is not well…
Background An important limitation of polymer-coated vascular stents, especially drug eluting, is slow endothelialization, which has been suggested as a potential cause of late stent thrombosis. Active capture of endothelial…
Background Drug-eluting bioabsorbable stents (DEBSs) represent a new device-based therapy for coronary artery disease. It has been reported that the stented segment becomes reendothelialized after 1 month and the segments…
Background The presence of end-stage renal disease (ESRD) after percutaneous coronary interventions (PCIs) is associated with poor outcomes, but the specific contribution of diabetes mellitus (DM) is not established. Methods…
Background Endovascular treatment has been used increasingly for the treatment of carotid artery stenosis. Studies of carotid artery stenting have shown conflicting results. Methods To address this disparity, we reviewed…
Background Popliteal aneurysms (PAs) are the most frequent peripheral artery aneurysms, and those of more than 2 cm in diameter are considered candidates for elective surgery. Although the standard treatment…
Background Optimal timing and mode of treatment for patients with coarctation of the aorta (COA) remain controversial, particularly in children. Surgery, balloon dilatation and stent implantation have all proven effective…
