Introduction Opioid use disorder (OUD) with injection drug use has reached epidemic levels with endocarditis as a major potential medical complication increasing the risk of mortality. There has been an…
Introduction Despite modern advances in the diagnosis and management of infective endocarditis (IE), inpatient mortality rate for patients with IE remains high at 15%–20% [ ]. In IE patients with…
Introduction Current European Society of Cardiology (ESC) and American College of Cardiology (ACC)/American Heart Association (AHA) guidelines for the diagnosis and management of infective endocarditis (IE) require the association of…
Introduction The postoperative course of patients with infective endocarditis is marked by relatively high mortality, with increased risk of severe complications leading to prolonged intensive care unit (ICU) and hospital…
Introduction In-hospital mortality for patients with infective endocarditis (managed medically and/or surgically) remains high, ranging from 10% to 20% [ ]. At 6 months, nearly 30% of patients will have…
Epidemiology Introduction The clinical features of infective endocarditis were first described in the 16th century by Jean François Fernel, a French physician who first introduced the term ‘physiology’ to describe…
Introduction Incidence of infective endocarditis (IE) continues to increase, with an estimated 15 cases per 100,000 people in the United States in 2018. Gram-positive cocci are most frequently the source…
Infective endocarditis (IE) is a rare disease but with devastating consequences. In-hospital mortality rates of left-sided endocarditis are around 20%, and 5-year mortality rates are up to 40% despite the…
Introduction With significant changes to the epidemiology of infective endocarditis (IE) in recent years, it is important to highlight which pathogens are the major causes of this disease. In the…
Introduction The diagnosis of infectious endocarditis is quite often complex and may be among the most challenging diagnoses facing today’s medical providers. Patients can present with a multitude of clinical…
