Home Monitoring of Blood Pressure
Despite the fact that conventional measurement of blood pressure (BP) in the office (OBP) has been the cornerstone for hypertension diagnosis and management for decades, it is recognized that this…
The Environment and High Blood Pressure
Hypertension is a polygenetic disorder provoked by remediable (e.g., sodium intake) as well as unmodifiable factors (e.g., aging). It accounts for up to half of cardiovascular events and is the…
Pathogenesis of Hypertension
Acknowledgments The authors’ research was supported by grants from the National Heart, Lung and Blood Institute (PO1 HL51971), National Institute of General Medical Sciences (P20 GM104357), National Institute of Diabetes…
Genetics of Hypertension
Hypertension genetics is of interest to different health care professionals: The clinician is often embarrassed by patient questioning on the origins of the blood pressure (BP) elevation in the absence…
Hypertension in South Asians
Elevated blood pressure (BP) is a growing health problem in South Asia, where it is the second largest risk factor for disability-adjusted life years lost, predominantly because of its strong…
Hypertension in Latin/Hispanic Population
Acknowledgments This work was supported by PI14/01841 grant from Instituto de Salud Carlos III and FONDOS FEDER. The term Hispanic or Latino refers to a person of Cuban, Mexican, Puerto…
Hypertension in East Asians and Native Hawaiians
With the changes in lifestyle and increasing longevity, the prevalence of hypertension increases worldwide. However, several classes of efficacious antihypertensive drugs are readily available for the management of hypertension in…
General Population and Global Cardiovascular Risk Prediction
Systemic arterial hypertension is the condition of persistent, nonphysiologic elevation of systemic blood pressure (BP). It is typically defined as a resting systolic BP (SBP) 140 mm Hg or higher,…
Perioperative Genomics
Abstract Preliminary candidate gene and genome-wide association studies (GWAS) suggest that susceptibility to adverse perioperative events, including cardiac (myocardial infarction, ventricular dysfunction, atrial fibrillation), neurologic, and renal (among others) is…
Cardiovascular Pharmacogenetics
Abstract This chapter will apply the principles and concepts introduced in the “Pharmacogenetics and Pharmacogenomics” chapter in volume 2, namely, discussion of four classes of genetic variants that underlie drug…
