Abstract In spite of many studies, the real nature, etiology, pathobiology, and therapy of acute exacerbation (AEx) of idiopathic pulmonary fibrosis (IPF) are not clear. It seemed that AEx-IPF may…
Abstract The care of patients with idiopathic pulmonary fibrosis requires multidisciplinary management integrating disease-specific therapy with treatment of comorbidities as well as symptom palliation. This review focuses on the role…
Abstract Idiopathic pulmonary fibrosis (IPF) is the most studied interstitial lung disease regarding symptom burden and perceived benefits and barriers to use of palliative care. Patients are without disease-reversing treatment…
Abstract In 2000, the American Thoracic Society and European Respiratory Society published the first consensus statement providing guidelines on the diagnosis and treatment of idiopathic pulmonary fibrosis (IPF). This statement…
Abstract Idiopathic pulmonary fibrosis (IPF) is a relentlessly progressive and inevitably fatal lung disease. Although the etiology and pathogenesis of IPF remain incompletely understood, two drugs (e.g., pirfenidone and nintedanib)…
Abstract Comprehension of the pathobiology of any disease is crucial to identifying the cellular and molecular mechanisms through which that disease arises and evolves. This may lead to the discovery…
Abstract Technological advances have led to an explosion of genetic discoveries, shedding new light on the underlying pathogenesis of interstitial lung disease (ILD). Identification of the genetic etiology provides a…
Acknowledgments The authors would like to thank members of the Blood Pressure Lowering Treatment Trialists’ Collaboration: L. Agodoa (National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of…
United States of America Hypertension Guidelines (Portion) Background Story The groundwork for the first United States hypertension guideline began with the first randomized trial of hypertension treatment in U.S. veterans,…
Background The term “guideline” needs to be defined before any meaningful discussion can occur about their need and more importantly, interpretation. “Guideline” was originally defined as “a cord or rope…
