Tobacco Control and Primary Prevention
Abstract Tobacco is the single greatest contributor to development of lung cancer. Nearly all societies across the globe are afflicted with the tobacco epidemic, and smoking rates are rising for…
Lung Cancer in Never-Smokers: A Different Disease
Abstract Major clinical, ethnic, gender, and histology differences between lung cancers arising from smokers and never-smokers, coupled with their different etiologic factors and major molecular differences, indicate that they represent…
Assessing and Treating Tobacco Use in Lung Cancer Care
Summary of Key Points • Addressing tobacco dependence in patients with cancer increases the quality of care by reducing their risk for treatment complications, improving their prognosis, and reducing the…
Classic Epidemiology of Lung Cancer
Abstract Lung cancer remains the highest contributor to cancer mortality worldwide. Among woman, lung cancer incidence and mortality is still increasing in many countries. The epidemiology of lung cancer is…
Histopathologic Approach to the Surgical Lung Biopsy in Interstitial Lung Disease
Abstract Interpretation of lung biopsy specimens is an integral part in the diagnosis of interstitial lung disease (ILD). The process of evaluating a surgical lung biopsy for disease involves answering…
Interstitial Lung Disease in the Connective Tissue Diseases
Abstract The connective tissue diseases (CTDs) are inflammatory, immune-mediated disorders in which interstitial lung disease (ILD) is common and clinically important. ILD may be the first manifestation of a CTD…
Idiopathic Pulmonary Fibrosis: Phenotypes and Comorbidities
Abstract Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and ultimately fatal disease of the lung with an unknown etiology and few treatment options. Recognition of patients who fall into…
Smoking-Related Interstitial Lung Diseases
Abstract Cigarette smoke is recognized as the primary causative agent of certain interstitial lung diseases (ILDs), namely respiratory bronchiolitis–associated ILD, desquamative interstitial pneumonia, and pulmonary Langerhans cell histiocytosis. Cigarette smoking…
Approach to the Diagnosis of Interstitial Lung Disease
Abstract Interstitial lung diseases (ILDs) encompass a wide range of diffuse pulmonary disorders, characterized by a variable degree of inflammatory and fibrotic changes of the alveolar wall and eventually the…
Lung Transplantation in Interstitial Lung Disease
Keywords Diffuse parenchymal lung disease, Interstitial lung disease, Lung disease, Lung transplantation, Parenchymal lung disease, Pulmonary Langerhans cell histiocytosis Key Points • For selected parenchymal lung disease (DPLD) patients…
