Central Sleep Apnea
Introduction A central sleep apnea (CSA) results from a transient abolition of central respiratory drive to the respiratory muscles leading to cessation of airflow; this is most often due to…
Pulmonary Rehabilitation
Introduction Patients with advanced chronic respiratory disease frequently have distressing symptoms, limitations in exercise ability, and reductions in health and functional status that persist despite optimal pharmacologic management. Pulmonary rehabilitation…
Eosinophilic Lung Diseases
Introduction The eosinophilic lung diseases are a group of disorders ( Table 68-1 ) characterized by the presence and presumed pathogenetic role of eosinophils in the disease processes. They are…
End-of-Life Care in Respiratory Failure
Introduction Patients with acute, chronic, and acute-on-chronic respiratory failure often suffer from symptoms such as pain and dyspnea and have a high expected mortality rate. These patients may be aggressively…
Pulmonary Vasculitis
Introduction and Definitions Pulmonary vasculitis is a general term that encompasses a wide variety of individual disease entities, all of which share a unifying finding of inflammation and destruction of…
Pulmonary Complications of Primary Immunodeficiencies
Introduction Primary immune deficiency disorders (PIDDs) are disorders of the immune system that predispose individuals to infection and frequently malignancy and autoimmunity as well. Most PIDDs are inherited disorders. However,…
Consequences of Sleep Disruption
Introduction Disturbed sleep is increasingly being recognized as a major contributor to various deleterious health outcomes. Sleep deprivation is well known to impair cognition, mood, and memory, but more recent…
Diving Medicine
Introduction Diving and work in compressed air have produced occupational exposure to hazardous environments for over 100 years. In the past 60 years, diving has become a recreation for millions…
Drug-Induced Pulmonary Disease
Introduction Adverse drug reactions have been the object of intense scrutiny since the early 1990s and have been recognized as a top safety priority by health care quality improvement organizations…
Sarcoidosis
Introduction Sarcoidosis has been defined as a multisystem granulomatous disorder of unknown cause. Sarcoidosis affects the lung in over 90% of cases but can affect any part of the body….
