First-In-Human Experience of the New Fully Repositionable IMPERIA Delivery System to Implant the ALLEGRA Transcatheter Heart Valve in Patients With Severe Calcific Aortic Stenosis or Degenerated Surgical Bioprosthesis: Thirty-Day Results of the EMPIRE I Study

May 11, 2025 by in CARDIOLOGY Comments Off on First-In-Human Experience of the New Fully Repositionable IMPERIA Delivery System to Implant the ALLEGRA Transcatheter Heart Valve in Patients With Severe Calcific Aortic Stenosis or Degenerated Surgical Bioprosthesis: Thirty-Day Results of the EMPIRE I Study

Abstract Background The ALLEGRA (Biosensors International) transcatheter heart valve is a self-expanding supra-annular bovine pericardial aortic valve. A new delivery system (IMPERIA™, Biosensors International) has been designed which allows the…

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Flow Status-Based Predicted Prosthesis-Patient Mismatch in Patients Undergoing Transcatheter Aortic Valve Replacement With a Balloon-Expandable Valve

May 11, 2025 by in CARDIOLOGY Comments Off on Flow Status-Based Predicted Prosthesis-Patient Mismatch in Patients Undergoing Transcatheter Aortic Valve Replacement With a Balloon-Expandable Valve

Abstract Background Effective orifice area (EOA) is flow dependent. However, established methods for the assessment of predicted prosthesis-patient mismatch (PPM) do not consider flow status and therefore may underestimate the…

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The enigmatic role of SIRT2 in the cardiovascular system: Deciphering its protective and detrimental actions to unlock new avenues for therapeutic intervention

Apr 20, 2025 by in CARDIOLOGY Comments Off on The enigmatic role of SIRT2 in the cardiovascular system: Deciphering its protective and detrimental actions to unlock new avenues for therapeutic intervention

Highlights • Context-dependent protective and harmful effects of SIRT2 in various cardiovascular pathologies, including hypertrophy and vascular dysfunction. • SIRT2 is not solely a deacetylase but has diverse catalytic activities,…

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The global magnitude and temporal trend of hypertensive heart disease burden attributable to high sodium intake from 1990 to 2021

Apr 20, 2025 by in CARDIOLOGY Comments Off on The global magnitude and temporal trend of hypertensive heart disease burden attributable to high sodium intake from 1990 to 2021

Abstract Background The relationship between high sodium intake (HSI) and hypertensive heart disease (HHD) has been confirmed. However, notable regional disparities exist in implementing effective measures to control sodium intake….

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Transcatheter or surgical aortic valve replacement in high-risk patients. Insights from a third-world country

Apr 20, 2025 by in CARDIOLOGY Comments Off on Transcatheter or surgical aortic valve replacement in high-risk patients. Insights from a third-world country

Introduction Valvular Heart Disease (VHD) comprises rheumatic heart disease, calcific aortic valve disease, and degenerative mitral valve disease. It affects more than 75 million people worldwide and accounted for over…

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Linking psoriasis to atrial fibrillation: Insights from “Association between psoriasis and atrial fibrillation: A systematic review and meta-analysis”

Apr 20, 2025 by in CARDIOLOGY Comments Off on Linking psoriasis to atrial fibrillation: Insights from “Association between psoriasis and atrial fibrillation: A systematic review and meta-analysis”

Abstract Patients with psoriasis indeed face an elevated risk of developing atrial fibrillation (AF), underscoring the need for vigilant monitoring to facilitate early detection and intervention. Given the current body…

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Advancements, challenges, and innovative strategies in cardiac rehabilitation for patients with acute myocardial infarction: A systematic review

Apr 20, 2025 by in CARDIOLOGY Comments Off on Advancements, challenges, and innovative strategies in cardiac rehabilitation for patients with acute myocardial infarction: A systematic review

Abstract Objects To synthesize current evidence on the impact of cardiac rehabilitation (CR) on acute myocardial infarction (AMI) patients, explore the barriers to effective CR delivery, and evaluate the potential…

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