Thoracic Key

Bronchogenic Cysts Borislav A. Alexiev, M.D. Fabio R. Tavora, M.D., Ph.D. Allen P. Burke, M.D. Definition Bronchogenic cysts are uncommon congenital anomalies of foregut origin resulting from abnormal ventral budding…

Thymic Hyperplasia Borislav A. Alexiev, M.D. Allen P. Burke, M.D. Terminology Most thymic hyperplasia is the result of reactive lymphoid hyperplasia, frequently in the setting of autoimmune disease, notably myasthenia…

Thymic Cysts Borislav A. Alexiev, M.D. Allen P. Burke, M.D. Terminology Thymic cysts are relatively rare benign lesions. They comprise approximately two-thirds of anterior mediastinal cysts, but only 5% of…

Thymic Neuroendocrine Carcinomas/Tumors Borislav A. Alexiev, M.D. Anja C. Roden, M.D. Allen P. Burke, M.D. The histopathologic classification of primary neuroendocrine tumors (NETs) of the mediastinum is similar to that…

Miscellaneous Carcinomas of the Thymus Borislav Alexiev, M.D. Fabio R. Tavora, M.D., Ph.D. Undifferentiated Thymic Carcinoma Undifferentiated thymic carcinoma represents between 1% and 27% of thymic carcinomas.1,2,3,4,5,6,7 By definition, these…

Lymphoepithelioma-Like Carcinoma Borislav A. Alexiev, M.D. Allen P. Burke, M.D. Terminology Lymphoepithelioma-like carcinoma (LELC) of the thymus is a primary thymic carcinoma characterized by a syncytial growth of undifferentiated carcinoma…

Mucoepidermoid Carcinoma Borislav A. Alexiev, M.D. Fabio R. Tavora, M.D., Ph.D. Terminology Thymic mucoepidermoid carcinoma is a rare morphologic variant of primary thymic carcinoma characterized by the presence of squamous…

Basaloid Carcinoma of the Thymus Borislav A. Alexiev, M.D. Allen P. Burke, M.D. Terminology Thymic basaloid carcinoma is a rare subtype of thymic carcinoma, with < 40 cases published in…

Squamous Cell Carcinoma Borislav A. Alexiev, M.D. Fabio R. Tavora, M.D., Ph.D. Terminology Thymic squamous cell carcinoma shows features of squamous cell carcinoma as seen in other organs, with or…