Study evaluating dexmedetomidine in the acute treatment of electrical storm (SEDATE): Rationale and design

Jun 27, 2026 by in CARDIOLOGY Comments Off on Study evaluating dexmedetomidine in the acute treatment of electrical storm (SEDATE): Rationale and design
ABSTRACT Background Electrical storm (ES) is a clinical syndrome characterized by densely clustered ventricular arrhythmias and associated with substantial morbidity and mortality. Autonomic dysfunction is thought to play key role…
read more

Staged interventional strategies for acute ST-segment elevation myocardial infarction patient with multivessel disease: Rationale and design of a multicenter, randomized STAGED trial

Jun 27, 2026 by in CARDIOLOGY Comments Off on Staged interventional strategies for acute ST-segment elevation myocardial infarction patient with multivessel disease: Rationale and design of a multicenter, randomized STAGED trial
ABSTRACT Background Complete revascularization (CR) has been shown to reduce the risk of adverse cardiovascular events compared with culprit-only revascularization (COR) in acute ST-segment elevation myocardial infarction (STEMI) patients with…
read more

Design and rationale of the GUARD-OAC: A randomized controlled trial evaluating proton pump inhibitor cotherapy for gastrointestinal protection in patients requiring direct oral anticoagulants

Jun 27, 2026 by in CARDIOLOGY Comments Off on Design and rationale of the GUARD-OAC: A randomized controlled trial evaluating proton pump inhibitor cotherapy for gastrointestinal protection in patients requiring direct oral anticoagulants
ABSTRACT Background Direct oral anticoagulants (DOACs) are the cornerstone of thromboembolic prevention in patients with atrial fibrillation, venous thromboembolism, or other cardiovascular conditions. However, DOAC use is associated with an…
read more

Reproductive health outcomes of congenital heart disease survivors: A report from the congenital heart disease project to understand lifelong survivor experience (CHD PULSE study)

Jun 27, 2026 by in CARDIOLOGY Comments Off on Reproductive health outcomes of congenital heart disease survivors: A report from the congenital heart disease project to understand lifelong survivor experience (CHD PULSE study)
Highlights • Reproductive counseling is scarce for women with congenital heart disease (CHD). • Women with CHD were more likely to have children than men with CHD. • Severe CHD…
read more

Coevolutionary analysis of evidence and recommendations in STEMI clinical practice guidelines: A 33-year meta-research study of ACC, AHA, and ESC

Jun 27, 2026 by in CARDIOLOGY Comments Off on Coevolutionary analysis of evidence and recommendations in STEMI clinical practice guidelines: A 33-year meta-research study of ACC, AHA, and ESC
ABSTRACT Background ST-Segment Elevation Myocardial Infarction (STEMI) is considered the main cause of mortality and morbidity for decades globally. Regularly, cardiology-related medical organizations publish clinical practice guidelines (CPGs) to support…
read more

Integrating AI-ECG and point-of-care cardiac ultrasound for screening structural heart disease: A proof-of-concept study

Jun 27, 2026 by in CARDIOLOGY Comments Off on Integrating AI-ECG and point-of-care cardiac ultrasound for screening structural heart disease: A proof-of-concept study
Highlights • POCCUS performed by novice operators was feasible, rapid, and provided sufficient image quality for accurate interpretation in a high-volume outpatient setting. • A 2-tiered approach, with AI-ECG first…
read more

Intravascular ultrasound guidance for complex high-risk indicated procedures: The IVUS CHIP trial study design

Jun 27, 2026 by in CARDIOLOGY Comments Off on Intravascular ultrasound guidance for complex high-risk indicated procedures: The IVUS CHIP trial study design
Abstract Background Intravascular ultrasound (IVUS) guidance for percutaneous coronary intervention (PCI) has been associated with a reduction in clinical events. Whereas most evidence is generated in Asian-Pacific populations, its global…
read more
Get Clinical Tree app for offline access