Remote dietitian counseling with short-term meal delivery improves DASH diet adherence and lowers blood pressure in veterans with hypertension and obesity

Jun 27, 2026 by in CARDIOLOGY Comments Off on Remote dietitian counseling with short-term meal delivery improves DASH diet adherence and lowers blood pressure in veterans with hypertension and obesity
Highlights • Motivational interviewing tailors counseling to unique preferences and motivations. • Remote motivational interviewing dietitian counseling sustainably improved DASH adherence and blood pressure. • Medically-tailored meals may have increased…
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Integration of a task strengthening strategy for hypertension management into HIV care in Nigeria: Baseline characteristics of participants in a cluster randomized controlled trial

Jun 27, 2026 by in CARDIOLOGY Comments Off on Integration of a task strengthening strategy for hypertension management into HIV care in Nigeria: Baseline characteristics of participants in a cluster randomized controlled trial
Highlights • 29.9% of screened HIV patients were found to have hypertension. • Over half of enrolled participants were overweight or obese (63.9%). • Only 25.8% continued prior antihypertension treatment….
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Physical rehabilitation for older patients with acute HFpEF (REHAB-HFpEF) trial: Design and rationale

Jun 27, 2026 by in CARDIOLOGY Comments Off on Physical rehabilitation for older patients with acute HFpEF (REHAB-HFpEF) trial: Design and rationale
ABSTRACT Rationale Older patients hospitalized for acute decompensated heart failure with preserved ejection fraction (HFpEF) experience persistently poor outcomes, including physical disability, cognitive impairment, depression, impaired health-related quality of life…
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Design and rationale of the EMPagliflozin after Aortic Valve Replacement (EMPAVR) study: A randomized clinical trial

Jun 27, 2026 by in CARDIOLOGY Comments Off on Design and rationale of the EMPagliflozin after Aortic Valve Replacement (EMPAVR) study: A randomized clinical trial
ABSTRACT Introduction Left ventricular (LV) hypertrophy and dysfunction secondary to aortic stenosis (AS) are key components of the disease’s underlying pathophysiology. Previous trials suggest that up to 1/3 of patients…
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Design and rationale of the Impella®-protected cardiac surgery trial (IMPACT): A multicenter, single-arm pilot study in high-risk cardiac surgery patients

Jun 27, 2026 by in CARDIOLOGY Comments Off on Design and rationale of the Impella®-protected cardiac surgery trial (IMPACT): A multicenter, single-arm pilot study in high-risk cardiac surgery patients
ABSTRACT Background Cardiac surgery patients with severe preoperative left ventricular (LV) dysfunction are at high risk for poor postoperative outcomes including prolonged ventilation, renal failure and post-cardiotomy cardiogenic shock (PCCS)….
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Design and rationale of the prospective, randomized, controlled trial to assess the management of moderate aortic stenosis by clinical surveillance or transcatheter aortic valve replacement: The PROGRESS Trial

Jun 27, 2026 by in CARDIOLOGY Comments Off on Design and rationale of the prospective, randomized, controlled trial to assess the management of moderate aortic stenosis by clinical surveillance or transcatheter aortic valve replacement: The PROGRESS Trial
ABSTRACT Background For patients with moderate aortic stenosis (AS), current US guidelines recommend clinical surveillance every 1 to 2 years. However, moderate AS has been associated with increased morbidity and…
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Design and rationale of the clinical trial to obtain the highest efficacy of dual antiplatelet therapy after carotid artery stenting in high bleeding risk patients (CHET): A multicenter, randomized, open-label, superiority trial

Jun 27, 2026 by in CARDIOLOGY Comments Off on Design and rationale of the clinical trial to obtain the highest efficacy of dual antiplatelet therapy after carotid artery stenting in high bleeding risk patients (CHET): A multicenter, randomized, open-label, superiority trial
Graphical abstract Highlights • CHET trials are abbreviated DAPT after carotid stenting in high-bleeding-risk patients. • Randomized, multicenter design compares abbreviated DAPT→SAPT vs prolonged DAPT. • Primary: clinically significant bleeding;…
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Rationale, design, and baseline characteristicss of the effect of PCSK9 inhibition on cardiovascular risk in treated HIV infection: EPIC-HIV randomized clinical trial

Jun 27, 2026 by in CARDIOLOGY Comments Off on Rationale, design, and baseline characteristicss of the effect of PCSK9 inhibition on cardiovascular risk in treated HIV infection: EPIC-HIV randomized clinical trial
Highlights • EPIC-HIV is a clinical trial of the PCSK9 inhibitor alirocumab among adults with HIV. • The primary outcome is arterial inflammation assessed using 18 F-FDG PET/CT. • Assesses…
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Design and rationale of the COMPARE-TAVI 2 trial: An all-comers head-to-head comparison of Evolut FX+ and Sapien 3 Ultra Resilia transcatheter heart valves

Jun 27, 2026 by in CARDIOLOGY Comments Off on Design and rationale of the COMPARE-TAVI 2 trial: An all-comers head-to-head comparison of Evolut FX+ and Sapien 3 Ultra Resilia transcatheter heart valves
Highlights • Majority of previous studies have indicated more aortic regurgitation with self-expandable compared to balloon-expandable transcatheter heart valves (THVs). • COMPARE-TAVI 2 study question: Is the Evolut FX+ noninferior…
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